Results 221 to 230 of about 11,034,532 (299)

Effect of serum albumin on cardiac-related events in end-stage kidney disease with mitral regurgitation initial hemodialysis. [PDF]

Medicine (Baltimore)
Wang X, Luo Y, Tian X, Yuan L, Chen X, Liu L, Wang Y, Chen T.   +7 more
europepmc   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Could Serum CA125 Aid the Clinical Assessment of Volume Status of End-Stage Kidney Disease Patients Treated by Peritoneal Dialysis Patients?

Blood Purif
Nikitiuk BE, Davenport A.
europepmc   +1 more source

The effect of comorbidity and frailty on dietary intake and protein losses in end-stage kidney disease patients undergoing peritoneal dialysis. [PDF]

Sci Rep
Shaaker H, Eaton S, Davenport A.
europepmc   +1 more source

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

Sociodemographic factors associated with the utilisation of specialist palliative care in individuals with end-stage kidney disease: protocol for a scoping review. [PDF]

BMJ Open
Jameson E, Brown PP, Bruni A, Wassef M, Chang R, Milne K, Berry J, Bonares M.   +7 more
europepmc   +1 more source

Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics

Advanced Science, EarlyView.
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley   +1 more source

Urinary NGAL and trehalase predict end-stage kidney disease in ANCA-associated vasculitis: a prospective cohort study. [PDF]

Ren Fail
Qiu M, Guan M, Weng X, Zheng R, Chen J, Peng W.   +5 more
europepmc   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

Real-world off-label apixaban dosing and clinical outcomes in patients with heart failure and end-stage kidney disease. [PDF]

Medicine (Baltimore)
Im SI, Bae SH, Kim SJ, Kim BJ, Heo JH, Kim YN, Jung Y, Rim H, Cho SP, Park JH, Shin HS.   +10 more
europepmc   +1 more source