Results 111 to 120 of about 351,631 (301)

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Assessment of health-related quality of life and related factors in patients with chronic liver disease

Brazilian Journal of Infectious Diseases, 2015
Background and objectives: Assessing health-related quality of life is an important aspect of clinical practice. Thus, the present study attempts to assess the health-related quality of life of patients with chronic liver disease.
Neila Paula de Souza, Livia Melo Villar, Artênio José Ísper Garbin, Tânia Adas Saliba Rovida, Cléa Adas Saliba Garbin   +4 more
doaj   +1 more source

Pharmacotherapy for Nonalcoholic Fatty Liver Disease

, 2015
Lifestyle modifications and optimization of the management of cardiometabolic comorbidities are currently the mainstay of treatment for patients with nonalcoholic fatty liver disease.
Chalasani, Naga, Gawrieh, Samer
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Mind the Model for End-Stage Liver Disease: Model for End-Stage Liver Disease Score as an Indicator of Hemoderivate Transfusion and Survival in Liver Transplantation

, 2015
La escasez de donantes de hígado ha aumentado la necesidad de seleccionar cuidadosamente a los receptores para mejorar los resultados del trasplante hepático.
Justo Alonso, Iago, Martín Municio, Ángel, Pulido Manzanero, José, Marcacuzco Quinto, Alberto Alejandro, Loinaz Segurola, Carmelo, Caso Maestro, Óscar, Cambra Molero, Félix, Jiménez Romero, Luis Carlos   +7 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Cluster analysis of Model for End-stage Liver Disease and European System for Cardiac Operative Risk Evaluation for predicting operative mortality after concomitant tricuspid valve surgeryCentral MessagePerspective

JTCVS Structural and Endovascular
Objective: Patients requiring concomitant tricuspid surgery represent a heterogeneous cohort with significant comorbidities and varying degrees of organ and right ventricular dysfunction.
Kevin Lim, FRCS (Ed), Antony Chin Ching Au, MB ChB, Matthew Ming Hon Hui, MRCS (Ed), Ivan Chi Hin Siu, MRCS (Ed), Simon Chi Ying Chow, FRCS (Ed), Jacky Yan Kit Ho, FRCS (Ed), Song Wan, FRCS (Ed), FACC, Randolph Hung Leung Wong, FRCS (Ed)   +7 more
doaj   +1 more source

Atrial fibrillation in hospitalized patients with end‐stage liver disease: temporal trends in prevalence and outcomes

, 2020
BACKGROUND & AIMS: End-stage liver disease (ESLD) happens due to the development and progression of chronic liver disease. This study aims to investigate the temporal trend, patient characteristics, and outcomes of atrial fibrillation (AF) in ...
Yu, Yamei,, Yingyi Qin, Jia He, Han, Hedong,, Yang Cao, Guo, Honglei,, Cao, Yang,, Honglei Guo, Yiming Ruan, Ruan, Yiming,, Wei, Xin,, Hedong Han, Yamei Yu, Xin Wei, Qin, Yingyi,, He, Jia,   +15 more
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source