Results 41 to 50 of about 22,655,126 (310)

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

Sedum shunhuangense (Crassulaceae), a new species from Hunan, China [PDF]

open access: yesPhytoKeys
We describe and illustrate Sedum shunhuangense, a new species from Hunan, China. The species is morphologically similar to S. alfredii and S. yangjifengensis but differs in having subequal sepals, papillate seeds, and alternate leaves with caducous lower
Zi-Lin Feng   +5 more
doaj   +3 more sources

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

open access: yesAdvanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer   +12 more
wiley   +1 more source

Gut microbiota: a new frontier in understanding and protecting endangered plateau schizothorax fish

open access: yesFrontiers in Microbiology
IntroductionAgainst the backdrop of global biodiversity decline, the role of gut microbiota in endangered species conservation remains underexplored. Endemic fish species in Xizang are critical to plateau ecosystems, yet many face severe survival threats.
Hongbo Pan   +11 more
doaj   +1 more source

Conservation of the endangered freshwater mussel Solenaia carinata (Bivalvia, Unionidae) in China

open access: yesNature Conservation, 2018
Despite the diversity and economic and ecological value of freshwater mussels, relatively little is known about their biology (especially for species outside of Europe and North America).
Yan-Ling Cao   +7 more
doaj   +3 more sources

Geolocators reveal migration and pre-breeding behaviour of the critically endangered Balearic Shearwater Puffinus mauretanicus [PDF]

open access: yes, 2012
Using combined miniature archival light and salt-water immersion loggers, we characterise the year-round individual at-sea movements of Europe’s only critically endangered seabird, the Balearic shearwater Puffinus mauretanicus, for the first time ...
Jones, A.   +31 more
core   +1 more source

Compound Abrus cantoniensis Extract Alleviates AFB1‐Induced Liver Injury by Regulating PI3K‐AKT Pathway and Gut Microbiota/Butyrate Metabolism

open access: yesAdvanced Science, EarlyView.
ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu   +12 more
wiley   +1 more source

Endangered Turkic languages of China [PDF]

open access: yes, 2016
A comprehensive survey, description and analysis of the endangered Turkic languages of ...
Dwyer, Arienne M.
core   +1 more source

Development and validation of a species-specific environmental DNA (eDNA) primer for endangered Asian arowana, Scleropages formosus (Teleostei: Osteoglossidae) for law enforcement and wild population monitoring

open access: yesMethodsX
The Asian Arowana, Scleropages formosus (Müller and Schlegel, 1844) is a large majestic freshwater teleost, crowned as the king of aquariums with its bright charismatic appearance and magnificent swimming performance.
Nurul Affiqah Edora Mohd-Azhar   +6 more
doaj   +1 more source

One‐Step Induction of Oogonia‐Like and Pro‐Spermatogonia‐Like Cells From Porcine Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study established a one‐step method inducing pro‐spermatogonia‐like (activating SOX17) and oogonia‐like (activating SOX17/TFAP2C) cells from porcine pgEpiSCs with a NANOS3‐tdTomato reporter. EGF activates the core PGC program and supports survival; BMP4 further induces NANOS3 and DDX4 expression; IWR1 enhances PGCLC efficiency by suppressing ...
Pengcheng He   +14 more
wiley   +1 more source

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