Results 21 to 30 of about 353,326 (262)

Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways

Frontiers in Genetics, 2015
The molecular basis of cancer and cancer multiple phenotypes are not yet fully understood. Next Generation Sequencing promises new insight into the role of genetic interactions in shaping the complexity of cancer.
Suleiman H Suleiman, Mahmoud E Koko, Wafaa H Nasir, Ommnyiah eElfateh, Ubai K Elgizouli, Mohammed O E Abdallah, Khalid O Alfarouk, Ayman eHussain, Shima eFaisal, Fathelrahman M A Ibrahim, Maurizio eRomano, Ali eSultan, Lawrence eBanks, Melanie eNewport, Francesco eBaralle, Ahmed M Elhassan, Hiba S Mohamed, Muntaser E Ibrahim   +17 more
doaj   +1 more source

Effect of Ramadan intermittent fasting on inflammatory markers, disease severity, depression, and quality of life in patients with inflammatory bowel diseases: A prospective cohort study

BMC Gastroenterology, 2022
Background Intermittent fasting (IF) during the month of Ramadan is part of the religious rituals of Muslims. The effect of intermittent fasting on disease activity in inflammatory bowel diseases (IBD) is still unknown.
Mohamed Negm, Ahmed Bahaa, Ahmed Farrag, Rania M. Lithy, Hedy A. Badary, Mahmoud Essam, Shimaa Kamel, Mohamed Sakr, Waleed Abd El Aaty, Mostafa Shamkh, Ahmed Basiony, Ibrahim Dawoud, Hany Shehab   +12 more
doaj   +1 more source

Molecular and morphological identification of Biomphalaria species from the state of São Paulo, Brazil

ZooKeys, 2017
DNA barcoding and morphological characters were used to identify adult snails belonging to the genus Biomphalaria from 17 municipalities in the state of São Paulo, Brazil.
Raquel Gardini Sanches Palasio, Marisa Cristina de Almeida Guimarães, Fernanda Pires Ohlweiler, Roseli Tuan   +3 more
doaj   +3 more sources

The early diagnostic value of serum neopterin and cartilage oligomeric matrix protein for osteoarticular changes among brucellosis patients at an early period

Journal of Orthopaedic Surgery and Research, 2018
Background Brucellosis is an important public health problem in China. Brucellosis can cause many osteoarticular changes, especially chronic brucellosis. Brucellosis presents various diagnostic difficulties because it mimics many other diseases.
Zhi-jun Zhao, Qiang Li, Li Ma, Ji-quan Li, Li-qing Xu   +4 more
doaj   +1 more source

Conceptualising quality early childhood education: Learning from young children in Brazil and South Africa through creative and play‐based methods

British Educational Research Journal, EarlyView., 2023
Abstract Early childhood has increasingly been acknowledged as a vital time for all children. Inclusive and quality education is part of the United Nations Sustainable Development Goals, with the further specification that all children have access to quality pre‐primary education.
Laura H. V. Wright, Irene Rizzini, Malibongwe Gwele, Lynn McNair, Cristina Laclette Porto, Marsha Orgill, E. Kay M. Tisdall, Malcolm Bush, Linda Biersteker   +8 more
wiley   +1 more source

A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism

Molecular Brain, 2022
Psychiatric disorders and neuroticism are closely associated with central nervous system, whose proper functioning depends on efficient protein renewal. This study aims to systematically analyze the association between anxiety / depression / neuroticism ...
Bolun Cheng, Xuena Yang, Shiqiang Cheng, Chun’e Li, Huijie Zhang, Li Liu, Peilin Meng, Yumeng Jia, Yan Wen, Feng Zhang   +9 more
doaj   +1 more source

Endemic in pandemic

The Pan-American Journal of Ophthalmology, 2021
Orbital mucormycosis is a dreaded condition and may lead to fatal intracranial infection if it spreads to the intracranial sinuses. The infection is caused by fungi of the order Mucorales. Rhizopus has been reported to be the causative pathogen.
Rajesh Subhash Joshi, Sonali Tamboli, Tanmay Surwade, Namrata Bansode, Ashwini Rasal, Pranshu Goel   +5 more
openaire   +2 more sources

Exploring the Potential Link Between Autoimmune Diseases and Pan-Cancer: A Multidatabase Mendelian Randomization Analysis

Journal of Immunology Research
Conclusions: This study provides evidence of a causal relationship between multiple AIDs and different cancer risks at the genetic level and provides a reference for the health management of patients with AIDs.
Chenguang Wang, Zhiyong Liu, Yuhao Zhou, Yan He, Yashu Zhang, Shiqi Chen, Wenqing Yang, Lijun Fan   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Prolonged Exposure to Elevated Iodine Levels in Drinking Water Is Associated With the Occurrence of Autoimmune Thyroid Disorders in Adults: Findings From a Case-Control Study Conducted in Shandong Province, China

Journal of Nutrition and Metabolism
Conclusions: The case-control study demonstrated a significant association between the development of AITD and prolonged exposure to elevated iodine levels (above 100 μg/L) in water. AITD was found to be associated with several other factors.
Yang Du, Peng Liu, Xu Huang, Fangang Meng, Lijun Fan, Weijia Li, Jinyin Yao, Xianglan Chen, Zhuowen Li, Ming Li, Chunpeng Lv, Wen Jiang, Wei Zhang, Dianjun Sun   +13 more
doaj   +1 more source