Results 1 to 10 of about 2,546,955 (257)

The case for a global therapeutics development coalition: Building a therapeutics pipeline for pandemic and endemic diseases [PDF]

PLOS Global Public Health
Esteban Burrone, Victor J. Dzau, Charles E Mowbray   +2 more
exaly   +2 more sources

Bioinformatics analysis for the identification of differentially expressed genes and related signaling pathways in H. pylori-CagA transfected gastric cancer cells [PDF]

PeerJ, 2021
Aim Helicobacter pylori cytotoxin-associated protein A (CagA) is an important virulence factor known to induce gastric cancer development. However, the cause and the underlying molecular events of CagA induction remain unclear.
Dingyu Chen, Chao Li, Yan Zhao, Jianjiang Zhou, Qinrong Wang, Yuan Xie   +5 more
doaj   +2 more sources

Iodine status five years after the adjustment of universal salt iodization: a cross-sectional study in Fujian Province, China

Nutrition Journal, 2021
Background Universal salt iodization program was introduced to China to eliminate iodine deficiency disorders in 1995. In 2012, Fujian Province decreased the concentration of iodized table salt according to the national unified requirement.
Yixuan Lin, Diqun Chen, Jiani Wu, Zhihui Chen   +3 more
doaj   +1 more source

CMMRD caused by PMS1 mutation in a sudanese consanguineous family

Hereditary Cancer in Clinical Practice, 2022
A consanguineous family of three siblings presented with different early onset pediatric cancers. Whole-exome sequencing of parents DNA revealed a deleterious frameshift mutation in hPMS1 the first to be reported in association to a CMMRD phenotype.
Reem S. Hamad, Muntaser E. Ibrahim
doaj   +1 more source

Occurrence of respiratory viruses among outpatients with diarrhea in Beijing, China, 2019–2020

Frontiers in Microbiology, 2023
ObjectivesTo investigate respiratory virus infections in diarrhea cases and identify the risk of respiratory virus transmission through feces.MethodsFecal specimens were collected from diarrhea cases in enteric disease clinics in Beijing, China, from ...
Lingyu Shen, Lingyu Shen, Hanqiu Yan, Weihong Li, Yi Tian, Changying Lin, Baiwei Liu, Yu Wang, Lei Jia, Daitao Zhang, Peng Yang, Quanyi Wang, Zhiyong Gao   +12 more
doaj   +1 more source

The Y chromosome ancestry marker R1b1b2: a surrogate of the SARS-CoV-2 population affinity

Human Genome Variation, 2021
Individual and population susceptibilities to disease remain a murky area of investigation, clouded by past bias based on ideological differences and wars. The current SARS-CoV-2 pandemic, the largest in living memory, brought this matter to forefront as
Muntaser Ibrahim, Abdalhameed Salih
doaj   +1 more source

Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways

Frontiers in Genetics, 2015
The molecular basis of cancer and cancer multiple phenotypes are not yet fully understood. Next Generation Sequencing promises new insight into the role of genetic interactions in shaping the complexity of cancer.
Suleiman H Suleiman, Mahmoud E Koko, Wafaa H Nasir, Ommnyiah eElfateh, Ubai K Elgizouli, Mohammed O E Abdallah, Khalid O Alfarouk, Ayman eHussain, Shima eFaisal, Fathelrahman M A Ibrahim, Maurizio eRomano, Ali eSultan, Lawrence eBanks, Melanie eNewport, Francesco eBaralle, Ahmed M Elhassan, Hiba S Mohamed, Muntaser E Ibrahim   +17 more
doaj   +1 more source

Selecting Hub Genes and Predicting Target Genes of microRNAs in Tuberculosis via the Bioinformatics Analysis

Genetics Research, 2021
Tuberculosis (TB) is the world's most prevalently infectious disease. Molecular mechanisms behind tuberculosis remain unknown. microRNA (miRNA) is involved in a wide variety of diseases. To validate the significant genes and miRNAs in the current sample,
Siqi Deng, Shijie Shen, Saeed El-Ashram, Huan Lu, Dan Luo, Guomin Ye, null Zhen feng, Bo Zhang, Hui Zhang, Wanjiang Zhang, Jiangdong Wu, Chuangfu Chen   +11 more
doaj   +1 more source

Is the urinary iodine/creatinine ratio applicable to assess short term individual iodine status in Chinese adults? Comparison of iodine estimates from 24-h urine and timed-spot urine samples in different periods of the day

Nutrition & Metabolism, 2022
Background Urinary iodine concentration (UIC) is routinely used to evaluate the population iodine status while the uniform method for the individual level assessment is uncertain.
Zhuan Liu, Yixuan Lin, Jiani Wu, Diqun Chen, Xiaoyan Wu, Ying Lan, Zhihui Chen   +6 more
doaj   +1 more source

Molecular and morphological identification of Biomphalaria species from the state of São Paulo, Brazil

ZooKeys, 2017
DNA barcoding and morphological characters were used to identify adult snails belonging to the genus Biomphalaria from 17 municipalities in the state of São Paulo, Brazil.
Raquel Gardini Sanches Palasio, Marisa Cristina de Almeida Guimarães, Fernanda Pires Ohlweiler, Roseli Tuan   +3 more
doaj   +3 more sources