Results 71 to 80 of about 1,257,075 (344)

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Metaphase Configurations in Drosophila: A Comparison of Endemic Hawaiian Species and Non-Endemic Species [PDF]

, 1976
The metaphase configurations of 400 strains from 63 species of Hawaiian Drosophila were determined from squash preparations of larval brain tissue or spermatogenic cells from adult testes.
Clayton, Frances E.
core   +2 more sources

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

Screening for chronic hepatitis C and chronic hepatitis B infections among pregnant females: a cross-sectional study

Egyptian Liver Journal, 2021
Background In Egypt, an endemic country for both viral hepatitis C and B infections, infection could be more prevalent in pregnant females. This study aimed to assess the prevalence of chronic HCV and HBV in a cohort of pregnant Egyptian females ...
Rasha Eletreby, Maged Abd Elraouf, Ahmed Fouad, Mona Nasser, Mostafa Al Bassiouni, Naglaa Zayed, Ayman Yosry, Zeinab Abdellatif   +7 more
doaj   +1 more source

Origin and diversification of Lake Ohrid’s endemic acroloxid limpets: the role of geography and ecology [PDF]

, 2016
Background: Ancient Lake Ohrid, located on the Albania-Macedonia border, is the most biodiverse freshwater lake in Europe. However, the processes that gave rise to its extraordinary endemic biodiversity, particularly in the species-rich gastropods, are ...
Albrecht, Christian, Föller, Kirstin, Shirokaya, Alena A., Stelbrink, Björn, Wilke, Thomas   +4 more
core   +1 more source

The geography of imported malaria to non-endemic countries: a meta-analysis of nationally reported statistics

Lancet. Infectious Diseases (Print), 2017
Summary Background Malaria remains a problem for many countries classified as malaria free through cases imported from endemic regions. Imported cases to non-endemic countries often result in delays in diagnosis, are expensive to treat, and can sometimes
A. Tatem, P. Jia, Dariya Ordanovich, M. Falkner, Zhuojie Huang, R. Howes, Simon Iain Hay, P. Gething, David L. Smith   +8 more
semanticscholar   +1 more source

scResponse: A Rank‐Based Method for Identifying Cell States That Contribute to Immunotherapy Response by Single‐Cell Data

Advanced Science, EarlyView.
Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong, Haijun Huang, Yuxiu Wang, Bo Jiang, Yuzheng Chen, Huanhuan Xu, Jing Ren, Shengnan Guo, Tianhao Li, Mingjie Zhang, Tianyu Zhai, Wenbo Yang, Kaidong Liu, Cheng Lyu, Jingxuan Kang, Mingshuo Zhang, Yupeng Lu, Binghui Si, Shujun Cao, Dandan Xu, Zong Chen, Dapeng Hao   +21 more
wiley   +1 more source

Differences between the intestinal microbial communities of healthy dogs from plateau and those of plateau dogs infected with Echinococcus

Virology Journal
Objective Cystic echinococcosis (CE) represents a profoundly perilous zoonotic disease. The advent of viral macrogenomics has facilitated the exploration of hitherto uncharted viral territories.
Jia Liu, Xiaojie Jiang, Wen Lei, Yuan Xi, Qing Zhang, Huixia Cai, Xiao Ma, Yufang Liu, Wei Wang, Na Liu, Xiongying Zhang, Wanli Ma, Cunzhe Zhao, Bin Ni, Wen Zhang, Yongshun Wang   +15 more
doaj   +1 more source

Challenges imposed by minor reference alleles on the identification and reporting of clinical variants from exome data

BMC Genomics, 2018
Background The conventional variant calling of pathogenic alleles in exome and genome sequencing requires the presence of the non-pathogenic alleles as genome references.
Mahmoud Koko, Mohammed O. E. Abdallah, Mutaz Amin, Muntaser Ibrahim   +3 more
doaj   +1 more source

CMMRD caused by PMS1 mutation in a sudanese consanguineous family

Hereditary Cancer in Clinical Practice, 2022
A consanguineous family of three siblings presented with different early onset pediatric cancers. Whole-exome sequencing of parents DNA revealed a deleterious frameshift mutation in hPMS1 the first to be reported in association to a CMMRD phenotype.
Reem S. Hamad, Muntaser E. Ibrahim
doaj   +1 more source