Results 101 to 110 of about 213,375 (263)

Endemic aleutian disease [PDF]

, 2017
Aleutian disease (AD) is a common global disease in farmed mink caused by infection with Aleutian disease virus (ADV). This thesis investigated the use of ADV antibody ELISA as a tool to reduce the impact on welfare and reproduction of mink in ADV endemic areas. First, two ELISA systems were compared.
openaire  

Health System Resilience and Afghan Refugee Health in Pakistan: An Exploratory Study of Challenges and Pathways to Inclusion

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Pakistan has hosted Afghan refugees for more than four decades, in one of the world's most protracted displacements of people. Afghan refugees receive health services through United Nations High Commissioner for Refugees (UNHCR) and non‐governmental organisation (NGO) supported programmes alongside public sector facilities at every tier.
Zahid Ali Memon, Asma Ummad, Amina Olabi, Natasha Palmer, Sophie Witter   +4 more
wiley   +1 more source

Single‐cell profiling of peripheral blood reveals acute‐phase immune dysregulation in human scrub typhus

iMeta, EarlyView.
Integrated single‐cell RNA sequencing, spectral flow cytometry, immune‐receptor repertoire profiling, and plasma proteomics revealed coordinated peripheral immune remodeling during acute scrub typhus. Patients exhibited expansion of cytotoxic, clonally amplified CD8+ T cells with exhaustion‐associated features, depletion and apoptosis of CD4+ T cells ...
Yijia Guo, Yi Niu, Nihui Zhang, Xiao Han, Liyuan Zhang, Yongguo Du, Lifen Han, Xiuying Tian, Zhao Xu, Gaoyu Wang, Kwok‐Yung Yuen, Jasper Fuk‐Woo Chan, Dahua Xu, Feifei Yin   +13 more
wiley   +1 more source

Assessing trends in clonorchiasis incidence via prescription data analysis in South Korea

BMC Public Health
Background While most parasitic diseases are being eradicated, clonorchiasis remains endemic and continues to pose a significant public health burden in South Korea.
Taeksang Lee, Jun Hyun Lee, Hanna Jin, Yun Kyung Lee, Hyun Beom Song   +4 more
doaj   +1 more source

Elevated Hemoglobin A2: A Molecular Revisited, and Implications to β‐Thalassemia Screening

Journal of Clinical Laboratory Analysis, EarlyView.
In Thailand, the Hb A2 cut‐off value for β‐thalassemia carrier has been changed from 4.0% to 3.6% since 2015. We examined the molecular basis of β‐thalassemia in a large cohort of Thai subjects with this change. The molecular basis of β‐thalassemia was updated, and a change in the Hb A2 cut‐off can alter this spectrum.
Kritsada Singha, Anupong Pansuwan, Hataichanok Srivorakun, Attawut Chaibunruang, Supawadee Yamsri, Wanicha Tepakhan, Kanokwan Sanchaisuriya, Goonnapa Fucharoen, Supan Fucharoen   +8 more
wiley   +1 more source

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass, Simon Swift, Saeid Baroutian   +2 more
wiley   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

Isorhamnetin Attenuates Isoproterenol-Induced Myocardial Injury by Reducing ENO1 (Alpha-Enolase) in Cardiomyocytes

Antioxidants
The protective effect of isorhamnetin on myocardial injury induced by isoproterenol (ISO) was investigated to identify the key targets and pathways involved, offering potential therapeutic insights for cardiovascular diseases.
Zhenli Guo, Shizhong Liu, Xianghong Hou, Xin Zhou, Yan Wang, Yi Rong, Xinzhi Li, Rui Yang, Ketao Ma   +8 more
doaj   +1 more source

Systematic Review of AI‐Driven Applications for Screening Nasopharyngeal Carcinoma Using MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Nasopharyngeal carcinoma (NPC) can be detected early on MRI, but adoption for screening is limited by a shortage of experienced specialists. MRI artificial intelligence (AI) algorithms for diagnosing NPC in the literature may address this, but most studies focus on routine clinical care, and their applicability in screening requires
Lun M. Wong, Ho Sang Leung, Zuyao Yang, Yip Man Tsang, Yuet Ting Chan, Tiffany Y. So, Ann D. King, Qi Yong H. Ai   +7 more
wiley   +1 more source

Carfilzomib Induces Cardiotoxicity by Blocking Autophagic Flux Through the cGAS-STING Signaling Pathway

Biomolecules
Carfilzomib (CFZ) is a proteasome inhibitor primarily used to treat relapsed and refractory multiple myeloma. However, its clinical application is limited by significant cardiotoxicity, the underlying mechanisms of which remain incompletely understood ...
Shizhong Liu, Xianghong Hou, Daiqianhui Li, Zhenli Guo, Xin Zhou, Yan Wang, Ketao Ma, Rui Yang, Xinzhi Li   +8 more
doaj   +1 more source