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Endemic Mycoses: Epidemiology and Diagnostic Strategies
Expert Review of Anti-Infective Therapy, 2020The global frequency of endemic mycoses has considerably increased, mainly due to environmental changes, population growth in endemic areas, and the increase in HIV-related immunosuppressed status. Among the most frequent endemic mycoses are coccidioidomycosis in semi-desert climates, and paracoccidioidomycosis, and histoplasmosis in tropical climates.
Gloria M González +2 more
exaly +3 more sources
The Lancet Infectious Diseases, 2017
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous implantation is also an important source of infections. Environmental exposure to spores of pathogenic fungi can result in subclinical and unrecognised syndromes, allergic manifestations, and even overt disease.
Flavio, Queiroz-Telles +5 more
openaire +2 more sources
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous implantation is also an important source of infections. Environmental exposure to spores of pathogenic fungi can result in subclinical and unrecognised syndromes, allergic manifestations, and even overt disease.
Flavio, Queiroz-Telles +5 more
openaire +2 more sources
Cutaneous Manifestations of Endemic Mycoses
Current Infectious Disease Reports, 2013All of the endemic mycoses have cutaneous and mucocutaneous manifestations that are most commonly seen when patients have disseminated infection. Biopsy of skin lesions is simple and safe and can assist in making a timely diagnosis of disseminated infection.
Jeannina A, Smith +2 more
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Approach to the Diagnosis of the Endemic Mycoses
Clinics in Chest Medicine, 2009The endemic mycoses are often overlooked in the evaluation of community-acquired pneumonia, and appropriate testing is not performed until the patient has failed to improve on antibacterial therapy. Antigen detection and fungal serology may be helpful in diagnosis of endemic mycoses as causes for pneumonia.
exaly +3 more sources
Seminars in Pediatric Infectious Diseases, 1998
Fungal infections are seen with increasing frequency in the pediatric age group. Aspergillus fumigatus, Coccidioides immitis, Cryptococcus neoformans, Blastomyces dermatitidis, and Histoplasma capsulatum all have a spectrum of illness ranging from asymptomatic exposure to significant pulmonary and disseminated disease.
Christine R. Kincaid +2 more
openaire +1 more source
Fungal infections are seen with increasing frequency in the pediatric age group. Aspergillus fumigatus, Coccidioides immitis, Cryptococcus neoformans, Blastomyces dermatitidis, and Histoplasma capsulatum all have a spectrum of illness ranging from asymptomatic exposure to significant pulmonary and disseminated disease.
Christine R. Kincaid +2 more
openaire +1 more source
Diagnosis of Midwestern Endemic Mycoses
Current Fungal Infection Reports, 2016Histoplasmosis and blastomycosis are the two most common midwestern endemic mycoses. A history of exposure to the geographic areas in which these organisms occur is central to raising suspicion for an endemic fungal infection. For infection with these organisms, the diagnosis is definitively established by recovery of the organism in tissue or body ...
Marisa H Miceli, Carol A Kauffman
exaly +2 more sources
Endemic mycoses in patients with hematologic malignancies
Seminars in Respiratory Infections, 2002Histoplasmosis, blastomycosis, and coccidioidomycosis are uncommon, but often life-threatening infections in patients who have hematologic malignancies. Disease occurs either as a result of new infection after an environmental exposure or as a result of reactivation of a remote infection.
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Newer Developments in Therapy for Endemic Mycoses
Clinical Infectious Diseases, 1994In the 1960s and 1970s, amphotericin B was the only effective therapy for serious systemic endemic fungal infections due to Histoplasma capsulatum, Blastomyces dermatitidis, and Sporothrix schenckii. In the 1980s, ketoconazole was introduced as therapy for endemic mycoses; after this antifungal agent was introduced, some of these infections could be ...
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Endemic Mycoses: Blastomycosis, Histoplasmosis, and Sporotrichosis
Infectious Disease Clinics of North America, 2006The endemic mycoses are diverse group of fungi that share several characteristics. They are able to cause disease in healthy hosts, they each occupy a specific ecologic niche in the environment, and they exhibit temperature dimorphism, existing as molds in the environment at temperature of 25 degrees C to 30 degrees C, and as yeasts, or spherules in ...
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The Journal of antimicrobial chemotherapy, 1999
Endemic mycoses remain a major public health problem in several countries and they are becoming increasingly frequent with the spread of HIV infection. Amphotericin B remains the drug of choice during the acute stage of life-threatening endemic mycoses occurring in both immunocompetent and immunocompromised hosts.
Lortholary, Olivier +2 more
openaire +2 more sources
Endemic mycoses remain a major public health problem in several countries and they are becoming increasingly frequent with the spread of HIV infection. Amphotericin B remains the drug of choice during the acute stage of life-threatening endemic mycoses occurring in both immunocompetent and immunocompromised hosts.
Lortholary, Olivier +2 more
openaire +2 more sources