Results 61 to 70 of about 1,829,608 (298)

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

open access: yesAdvanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding   +7 more
wiley   +1 more source

Flora of vascular plants in the Chilgapsan Provincial Park, Korea

open access: yesJournal of Asia-Pacific Biodiversity, 2014
The flora of Chilgapsan Provincial Park in Cheongyang-gun (Chungcheongnam-do), Korea was surveyed from 2000 to 2014. In 19 field surveys, vascular plants were revealed 490 taxa belonging to 97 families, 309 genera, 433 species, four subspecies, 48 ...
Ro-Young Lee   +6 more
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

Harnessing Molecular Phylogeny and Chemometrics for Taxonomic Validation of Korean Aromatic Plants: Integrating Genomics with Practical Applications

open access: yesPlants
Plant genetics and chemotaxonomic analysis are considered key parameters in understanding evolution, plant diversity and adaptation. Korean Peninsula has a unique biogeographical landscape that supports various aromatic plant species, each with ...
Adnan Amin, Seonjoo Park
doaj   +1 more source

The IUCN Green Status of Species: A Call for Mediterranean Botanists to Contribute to This New Ambitious Effort

open access: yesPlants, 2022
In the Mediterranean Basin, a critical focal point for the conservation of plant diversity, there has been a large increase in practical conservation actions for many plant species to prevent extinction and to improve their conservation status ...
Donatella Cogoni   +4 more
doaj   +1 more source

Darwin and the plants of the Galapagos-Islands [PDF]

open access: yes, 2009
During his five year sea voyage with the “Beagle”, Darwin, at the suggestion of the botanist J.S. Henslow, collected more than 1400 vascular plants, and more than 200 of them alone during his short stay on the Galápagos Islands.
Stöcklin, Jürg
core  

Incidence of symptomatic and asymptomatic Leishmania donovani infections in high-endemic foci in India and Nepal: a prospective study. [PDF]

open access: yes, 2011
Incidence of Leishmania donovani infection and Visceral Leishmaniasis (VL) was assessed in a prospective study in Indian and Nepalese high-endemic villages. DAT-seroconversion was used as marker of incident infection in 3 yearly surveys.
Ostyn Bart   +26 more
core   +2 more sources

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

open access: yesAdvanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen   +7 more
wiley   +1 more source

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

open access: yesAngewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley   +11 more
wiley   +2 more sources

Gastroprotective Activity of Parastrephia quadrangularis (Meyen), Cabrera from the Atacama Desert

open access: yesMolecules, 2018
Forty-three metabolites including several methoxylated flavonoids, tremetones, and ent-clerodane diterpenes were accurately identified for the first time in the ethanolic extract of P.
Alejandro Ardiles   +5 more
doaj   +1 more source

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