Results 151 to 160 of about 25,542 (192)
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Review of the Endocannabinoid System
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2021The endocannabinoid system (ECS) is a widespread neuromodulatory network involved in the developing central nervous system as well as playing a major role in tuning many cognitive and physiological processes. The ECS is composed of endogenous cannabinoids, cannabinoid receptors, and the enzymes responsible for the synthesis and degradation of ...
Hui-Chen, Lu, Ken, Mackie
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The endocannabinoid system in invertebrates
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 2002What is the role of the cannabinoid system in invertebrates and can it tell us something about the human system? We discuss in this review the possible presence of the cannabinoid system in invertebrates. Endocannabinoid processes, i.e., enzymatic hydrolysis, as well as cannabinoid receptors and endocannabinoids, have been identified in various species
M, Salzet, G B, Stefano
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The endocannabinoid system and migraine
Experimental Neurology, 2010The recently discovered endocannabinoid system (ECS), which includes endocannabinoids and the proteins that metabolize and bind them, has been implicated in multiple regulatory functions both in health and disease. Several studies have suggested that ECS is centrally and peripherally involved in the processing of pain signals.
GRECO R +3 more
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The Endocannabinoid System and the Brain
Annual Review of Psychology, 2013The psychoactive constituent in cannabis, Δ9-tetrahydrocannabinol (THC), was isolated in the mid-1960s, but the cannabinoid receptors, CB1 and CB2, and the major endogenous cannabinoids (anandamide and 2-arachidonoyl glycerol) were identified only 20 to 25 years later.
Raphael, Mechoulam, Linda A, Parker
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2021
The biological effects of marijuana, particularly Δ-9-THC, have led to the discovery of the endogenous endocannabinoid system in all vertebrate and invertebrate creatures. Ancient Chinese text, dated almost 5000 years, described the medicinal uses of cannabis.
Glenn R. Rech, Samer N. Narouze
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The biological effects of marijuana, particularly Δ-9-THC, have led to the discovery of the endogenous endocannabinoid system in all vertebrate and invertebrate creatures. Ancient Chinese text, dated almost 5000 years, described the medicinal uses of cannabis.
Glenn R. Rech, Samer N. Narouze
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The endocannabinoid system and psychiatric disorders
Experimental Neurology, 2010The present review summarizes the latest information on the role and the pharmacological modulation of the endocannabinoid system in mood disorders and its potential implication in psychotic disorders such as schizophrenia. Reduced functionality might be considered a predisposing factor for major depression, so boosting endocannabinoid tone might be a ...
Tiziana Rubino, Daniela Parolaro
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Imaging the endocannabinoid signaling system
Journal of Neuroscience Methods, 2022The endocannabinoid (eCB) system is one of the most widespread neuromodulatory systems in the mammalian brain, with a multifaceted role in functions ranging from development to synaptic plasticity. Endocannabinoids are synthesized on demand from membrane lipid precursors, and act primarily on a single G-protein coupled receptor type, CB1, to carry out ...
Barna, Dudok, Ivan, Soltesz
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The Endocannabinoid System and Anxiety
2017The medical properties of Cannabis sativa is known for centuries. Since the discovery and characterization of the endogenous cannabinoid system, several studies have evaluated how cannabinoid compounds and, particularly, how the modulation of the endocannabinoid (eCB) system influences a wide range of functions, from metabolic to mental disorders ...
S F, Lisboa +6 more
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Endocannabinoids and their Involvement in the Neurovascular System
Current Neurovascular Research, 2004Endocannabinoids are a new class of lipids, which include amides, esters and ethers of long chain polyunsaturated fatty acids. Anandamide (N-arachidonoylethanolamine; AEA) and 2-arachidonoylglycerol are the main endogenous agonists of cannabinoid receptors, able to mimic several pharmacological effects of Delta(9)-tetrahydrocannabinol, the active ...
Battista N, Fezza F, Maccarrone M
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Praxis, 2008
The endocannabinoid system is a physiological system, which is responsible for the control of glucose and lipid-metabolism, as well as for the regulation of the body weight. The endocannabinoid receptors are distributed both in the central and peripher nervous system.
I, Sudano, D, Périat, G, Noll
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The endocannabinoid system is a physiological system, which is responsible for the control of glucose and lipid-metabolism, as well as for the regulation of the body weight. The endocannabinoid receptors are distributed both in the central and peripher nervous system.
I, Sudano, D, Périat, G, Noll
openaire +3 more sources