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Role of the Endocannabinoid System in the Adipose Tissue with Focus on Energy Metabolism
The endocannabinoid system is involved in a wide range of processes including the control of energy acquisition and expenditure. Endocannabinoids and their receptors are present in the central nervous system but also in peripheral tissues, notably the ...
Nicolas Flamand +2 more
exaly +3 more sources
From endocannabinoid profiling to 'endocannabinoid therapeutics'
The discovery of the endocannabinoid signalling system, that is, of cannabinoid receptors, their endogenous ligands, known as endocannabinoids, and of endocannabinoid anabolic and catabolic enzymes, raised several questions regarding the ...
Petrosino S, Di Marzo V, Ligresti A
core +5 more sources
N-oleoylglycine (OlGly) is a lipid mediator that belongs to the expanded version of the endocannabinoid (eCB) system, the endocannabinoidome (eCBome), which has recently gained increasing attention from the scientific community for its protective effects
Anna Lauritano +9 more
doaj +1 more source
Acute respiratory distress syndrome (ARDS) is a serious inflammatory lung disorder and a complication of SARS-CoV-2 infection. In patients with severe SARS-CoV-2 infection, the transition to ARDS is principally due to the occurrence of a cytokine storm ...
Aniello Schiano Moriello +8 more
doaj +1 more source
The Endocannabinoid System: A Bridge between Alzheimer’s Disease and Gut Microbiota
Alzheimer’s disease (AD) is a neurodegenerative disease that progresses from mild cognitive impairment to severe dementia over time. The main clinical hallmarks of the disease (e.g., beta-amyloid plaques and neurofibrillary tangles) begin during ...
Tiziana Bisogno +2 more
doaj +1 more source
Bone is a highly complex and metabolically active tissue undergoing a continuous remodeling process, which endures throughout life. A complex cell-signaling system that plays role in regulating different physiological processes, including bone remodeling,
Magdalena Kostrzewa +6 more
doaj +1 more source
There is growing evidence that perturbation of the gut microbiome, known as “dysbiosis”, is associated with the pathogenesis of human and veterinary diseases that are not restricted to the gastrointestinal tract.
Aniello Schiano Moriello +2 more
doaj +1 more source
Statins are the most prescribed lipid-lowering agents worldwide. Their use is generally safe, although muscular toxicity occurs in about 1 in 10.000 patients.
Hilal Kalkan +9 more
doaj +1 more source
Endocannabinoids and Reproduction [PDF]
Infertility is a worldwide reproductive health problem whose consequences have deep psychological and social impact in health, demographic change, and wellbeing. Thus, the knowledge of basic, conserved modulators of reproduction might contribute to the discovery of new potential target for the exploitation of drugs to treat infertility in humans ...
Rosaria Meccariello +3 more
openaire +4 more sources
Disinhibition of orexin-A/hypocretin-1 (OX-A) release occurs to several output areas of the lateral hypothalamus (LH) in the brain of leptin knockout obese ob/ob mice.
Lea Tunisi +12 more
doaj +1 more source

