Results 41 to 50 of about 37,091 (247)
Frontiers in Synaptic Neuroscience, 2021 The endocannabinoid system is responsible for regulating a spectrum of physiological activities and plays a critical role in the developing brain. During adolescence, the endocannabinoid system is particularly sensitive to external insults that may ...
Danna Ellner +7 more
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, 2014 The spatial pattern of synapse activation may impact on synaptic plasticity. This applies to the synaptically-evoked endocannabinoid-mediated short-term depression at the parallel fiber (PF) to Purkinje cell synapse, the occurrence of which requires ...
Pachoud, B +10 more
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Endocannabinoids and epilepsy [PDF]
, 2015 The brain endocannabinoid system (ECS) plays an essential role in regulating central physiological processes that underlie learning and memory, anxiety, depression, addiction, appetite and feeding, pain, neuronal excitability and protection. A primary mode through which the ECS functions in the brain is via its regulation of synaptic transmission ...
Robert Blair +2 more
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Frontiers in Neuroanatomy, 2018 Hypocretins/Orexins neuropeptides are known to regulate numerous physiological functions, such as energy homeostasis, food intake, sleep/wake cycle, arousal and wakefulness, in vertebrates.
Roberta Imperatore +11 more
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Oromucosal Administration of a Cannabidiol-Enriched Cannabis sp. Extract for 2 Weeks Moderately Reduces Cold Hyperalgesia in Rats With Neuropathic Pain. [PDF]
Eur J PainABSTRACT Background Chronic neuropathic pain (CNP) involves complex interactions between resident and peripheral immune cells, as well as modulation of the endocannabinoid system. Cannabis‐based products have emerged as promising therapeutic options, but their effects on immune cells remain unclear.
Campos RMP +5 more
europepmc +2 more sources
The Endocannabinoid System: Overview, Therapeutic Applications and Future Perspectives
, 2021 The endocannabinoid system is an incredibly pervasive network, influencing the homeostasis of immune, cardiovascular, central nervous, and cutaneous systems, among many others. The biological effects of the endocannabinoid system were gleaned mostly from
Talab, Abdullah Abdulrahman
core
Endocannabinoids and the Heart [PDF]
Journal of Cardiovascular Pharmacology, 2009 Endocannabinoids, such as anandamide and 2-arachidonoylglycerol, are synthesized from membrane phospholipids in the heart and other cardiovascular tissues. They activate cannabinoid CB1 and CB2 receptors, transient receptor potential V1 (TRPV1), peroxisome proliferator-activated receptors, and perhaps a novel vascular G-protein-coupled receptor ...
openaire +2 more sources
BMC Veterinary Research, 2017 Background Cannabis-based drugs have been shown to be effective in inflammatory diseases. A number of endocannabinoids including N- arachidonoylethanolamide (anandamide, AEA) and 2-arachidonyl glycerol (2-AG) with activity at the cannabinoid receptors ...
Carmela Valastro +7 more
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OncoImmunology, 2021 Monoacylglycerol lipase (MGL) expressed in cancer cells influences cancer pathogenesis but the role of MGL in the tumor microenvironment (TME) is less known.
Melanie Kienzl +17 more
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The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers
International Journal of Endocrinology, 2013 The “endocannabinoid system (ECS)” comprises the endocannabinoids, the enzymes that regulate their synthesis and degradation, the prototypical cannabinoid receptors (CB1 and CB2), some noncannabinoid receptors, and an, as yet, uncharacterised transport ...
Thangesweran Ayakannu +4 more
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