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Role of the Endocannabinoid System in Fibromyalgia [PDF]

open access: yesCurrent Issues in Molecular Biology
Fibromyalgia is a chronic disease marked by extensive musculoskeletal pain, persistent fatigue, and cognitive impairments. Despite its high prevalence, the underlying pathological mechanisms of fibromyalgia are still not fully elucidated.
Mario García-Domínguez
doaj   +2 more sources

Endocannabinoid system: Potential novel targets for treatment of schizophrenia

open access: yesNeurobiology of Disease, 2013
Accumulating epidemiological evidences suggest that cannabis use during adolescence is a potential environmental risk for the development of psychosis, including schizophrenia.
Atsushi Saito   +4 more
doaj   +3 more sources

The Microbiome and Gut Endocannabinoid System in the Regulation of Stress Responses and Metabolism

open access: yesFrontiers in Cellular Neuroscience, 2022
The endocannabinoid system, with its receptors and ligands, is present in the gut epithelium and enteroendocrine cells, and is able to modulate brain functions, both indirectly through circulating gut-derived factors and directly through the vagus nerve,
Raj Kamal Srivastava   +3 more
doaj   +1 more source

Role of the Endocannabinoid System in the Adipose Tissue with Focus on Energy Metabolism

open access: yesCells, 2021
The endocannabinoid system is involved in a wide range of processes including the control of energy acquisition and expenditure. Endocannabinoids and their receptors are present in the central nervous system but also in peripheral tissues, notably the ...
Volatiana Rakotoarivelo   +2 more
doaj   +1 more source

The endocannabinoid system, cannabis, and cannabidiol: Implications in urology and men's health

open access: yesCurrent Urology, 2021
. Background:. The endocannabinoid system is a neuromodulatory system responsible for partial regulation of cognitive and emotional processes in the human central nervous system such as behavior, mood disorders, and neurologic disorders such as epilepsy.
Jillian L. Capodice, Steven A. Kaplan
doaj   +1 more source

Endocannabinoid system and periodontitis: mechanisms and therapeutic implications [PDF]

open access: yesRevista de Odontologia da UNESP, 2023
Introduction Periodontitis is a major public health problem. Although the principle of periodontitis therapy is mainly focused on removing dental biofilm and associated factors, its physiopathology enrolls different molecular and inflammatory events ...
Lélio Fernando Ferreira SOARES   +2 more
doaj   +1 more source

Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex. [PDF]

open access: yesPLoS ONE, 2007
Cannabinoids have deleterious effects on prefrontal cortex (PFC)-mediated functions and multiple evidences link the endogenous cannabinoid (endocannabinoid) system, cannabis use and schizophrenia, a disease in which PFC functions are altered. Nonetheless,
Mathieu Lafourcade   +5 more
doaj   +1 more source

The Endocannabinoid System and Cannabidiol: Past, Present, and Prospective for Cardiovascular Diseases

open access: yesPharmaceuticals, 2021
In the past, cannabis was commonly associated with mysticism and illegality. Fortunately, in recent years perspectives and discourses have changed. More prominence has been given to the rigorous scientific effort that led to the discovery of cannabis ...
Martina Rabino   +5 more
doaj   +1 more source

Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats

open access: yesBiology of Sex Differences, 2021
Background Several chronic pain disorders, such as migraine and fibromyalgia, have an increased prevalence in the female population. The underlying mechanisms of this sex-biased prevalence have yet to be thoroughly documented, but could be related to ...
Aidan Levine   +8 more
doaj   +1 more source

Mediterranean Diet and Neurodegenerative Diseases: The Neglected Role of Nutrition in the Modulation of the Endocannabinoid System

open access: yesBiomolecules, 2021
Neurodegenerative disorders are a widespread cause of morbidity and mortality worldwide, characterized by neuroinflammation, oxidative stress and neuronal depletion.
Federica Armeli   +4 more
doaj   +1 more source

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