Results 31 to 40 of about 25,542 (192)
The Endocannabinoid/Endovanilloid System and Depression [PDF]
Current Neuropharmacology, 2014 Depression is one of the most frequent causes of disability in the 21st century. Despite the many preclinical and clinical studies that have addressed this brain disorder, the pathophysiology of depression is not well understood and the available antidepressant drugs are therapeutically inadequate in many patients.
Smaga-Maślanka, Irena +4 more
openaire +3 more sources
Role of Cannabinoids in the Regulation of Bone Remodelling
Frontiers in Endocrinology, 2012 The endocannabinoid system plays a key role in regulating a variety of physiological processes such as appetite control and energy balance, pain perception, and immune responses. Recent studies have implicated the endocannabinoid system in the regulation
Aymen I Idris, Stuart H Ralston
doaj +1 more source
Endocannabinoid System and Synaptic Plasticity: Implications for Emotional Responses
Neural Plasticity, 2007 The endocannabinoid system has been involved in the regulation of anxiety, and proposed as an inhibitory modulator of neuronal, behavioral and adrenocortical responses to stressful stimuli.
María-Paz Viveros +3 more
doaj +1 more source
ROLE OF ENDOCANNABINOID RECEPTORS IN IMMUNE RESPONSE REGULATION
Медицинская иммунология, 2014 . Expression of endocannabinoid receptors (СВ1, СВ2) in immunocompetent cells was studied under the conditions of in vivo stimulation of immune system. Intracorporeal blood irradiation and enrichment of peripheral blood by ozone/oxygen mixture were used ...
E. G. Lobanova
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Exo- and Endo-cannabinoids in Depressive and Suicidal Behaviors
Frontiers in Psychiatry, 2021 Cannabis (marijuana) has been known to humans for thousands of years but its neurophysiological effects were sparsely understood until recently. Preclinical and clinical studies in the past two decades have indisputably supported the clinical proposition
Srinagesh Mannekote Thippaiah +5 more
doaj +1 more source
Engineered probiotics modulate the endocannabinoid system
Biotechnology NotesButyrate is a key microbial metabolite known to enhance host metabolic processes by reducing blood glucose levels and promoting energy metabolism, thereby potentially suppressing the risk of developing metabolic syndrome.
In Young Hwang +3 more
doaj +1 more source
Frontiers in Psychiatry, 2018 The use of cannabis is a well-established component risk factor for schizophrenia, particularly in adolescent individuals with genetic predisposition for the disorder.
Rose Chesworth +8 more
doaj +1 more source
Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition
Advanced Science, EarlyView.CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu +13 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl +10 more
wiley +1 more source