Results 31 to 40 of about 24,740 (199)
Endocannabinoid System and Synaptic Plasticity: Implications for Emotional Responses
Neural Plasticity, 2007 The endocannabinoid system has been involved in the regulation of anxiety, and proposed as an inhibitory modulator of neuronal, behavioral and adrenocortical responses to stressful stimuli.
María-Paz Viveros +3 more
doaj +1 more source
ROLE OF ENDOCANNABINOID RECEPTORS IN IMMUNE RESPONSE REGULATION
Медицинская иммунология, 2014 . Expression of endocannabinoid receptors (СВ1, СВ2) in immunocompetent cells was studied under the conditions of in vivo stimulation of immune system. Intracorporeal blood irradiation and enrichment of peripheral blood by ozone/oxygen mixture were used ...
E. G. Lobanova
doaj +1 more source
Exo- and Endo-cannabinoids in Depressive and Suicidal Behaviors
Frontiers in Psychiatry, 2021 Cannabis (marijuana) has been known to humans for thousands of years but its neurophysiological effects were sparsely understood until recently. Preclinical and clinical studies in the past two decades have indisputably supported the clinical proposition
Srinagesh Mannekote Thippaiah +5 more
doaj +1 more source
Frontiers in Psychiatry, 2018 The use of cannabis is a well-established component risk factor for schizophrenia, particularly in adolescent individuals with genetic predisposition for the disorder.
Rose Chesworth +8 more
doaj +1 more source
Endocannabinoid System in the Airways [PDF]
Molecules, 2019 Cannabinoids and the mammalian endocannabinoid system is an important research area of interest and attracted many researchers because of their widespread biological effects. The significant immune-modulatory role of cannabinoids has suggested their therapeutic use in several inflammatory conditions.
openaire +2 more sources
Annals of Neurology, EarlyView.Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl +10 more
wiley +1 more source
Circadian rhythms and chronotherapy in Alzheimer's disease: Mechanisms and therapeutic implications
Neuroprotection, EarlyView.Circadian dysregulation contributes to Alzheimer's disease through sleep disruption, clock‐gene dysfunction, neuroinflammation, impaired proteostasis, and metabolic imbalance. These alterations promote cognitive decline and disease progression, while circadian biomarkers and chronotherapeutic interventions offer opportunities for precision diagnosis ...
Bivek Singh +2 more
wiley +1 more source
Pharmaceuticals, 2010 There is an increasing recognition that the endocannabinoid system is the crucial cytokine-hormone system regulating early human pregnancy. The synchronous development of the fertilized embryo and the endometrium to ensure timely implantation has been ...
Justin C. Konje +7 more
doaj +1 more source
Pediatric Investigation, EarlyView.Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil +2 more
wiley +1 more source
PM&R, EarlyView.Abstract Objective To determine the dose–response relationship of a walking program and compare different delivery methods of walking exercise for patients with chronic low back pain (CLBP). Methods A systematic search of PubMed/MEDLINE, Web of Science, Scopus, Embase, and the Cochrane Library was conducted from inception to October 21, 2024.
Rodrigo Núñez‐Cortés +8 more
wiley +1 more source