Results 21 to 30 of about 24,740 (199)

Endocannabinoids and the haematological system [PDF]

open access: yesBritish Journal of Pharmacology, 2007
Endocannabinoids are blood borne and may also be secreted by the endothelium. Accordingly, there has been interest in the interactions between (endo)cannabinoids and blood cells. There is certainly evidence that (endo)cannabinoids may promote platelet activation, indicating that they may be thrombogenic.
openaire   +2 more sources

The Role of the Endocannabinoid System in Atherosclerosis [PDF]

open access: yesJournal of Neuroendocrinology, 2008
Our current understanding of the pathophysiology of atherosclerosis suggests a prominent role for immune responses from its initiation through its complications. Given the increasing prevalence of cardiovascular risk factors worldwide, there is an urgent need to better understand the underlying mechanisms to improve current treatment protocols.
Mach, François, Steffens, Sabine
openaire   +4 more sources

The Endocannabinoid System and Energy Metabolism [PDF]

open access: yesJournal of Neuroendocrinology, 2008
Many different regulatory actions have been attributed to endocannabinoids, and their involvement in several pathophysiological conditions is under intense scrutiny. Cannabinoid receptors [cannabinoid receptor type 1 (CB1) and CB2] participate in the physiological modulation of many central and peripheral functions.
Bellocchio L.   +3 more
openaire   +3 more sources

Gene expression of the endocannabinoid system in endometrium through menstrual cycle

open access: yesScientific Reports, 2022
Endocannabinoids mediate cellular functions and their activity is controlled by a complex system of enzymes, membrane receptors and transport molecules.
Keisuke Tanaka   +8 more
doaj   +1 more source

The Endocannabinoid/Endovanilloid System and Depression [PDF]

open access: yesCurrent Neuropharmacology, 2014
Depression is one of the most frequent causes of disability in the 21st century. Despite the many preclinical and clinical studies that have addressed this brain disorder, the pathophysiology of depression is not well understood and the available antidepressant drugs are therapeutically inadequate in many patients.
Smaga-Maślanka, Irena   +4 more
openaire   +3 more sources

Peripheral endocannabinoids regulate skeletal muscle development and maintenance

open access: yesEuropean Journal of Translational Myology, 2010
As a principal tissue responsible for insulin-mediated glucose uptake, skeletal muscle is important for whole-body health. The role of peripheral endocannabinoids as regulators of skeletal muscle metabolism has recently gained a lot of interest, as ...
Dongjiao Zhao   +6 more
doaj   +1 more source

Endocannabinoid System Alterations in Posttraumatic Stress Disorder: A Review of Developmental and Accumulative Effects of Trauma

open access: yesChronic Stress, 2019
The role of the endocannabinoid system in stress-related psychiatric symptoms has been investigated in many animal and human studies. Although most of these studies consistently report long-lasting effects of prolonged stress and trauma on the ...
Anahita Bassir Nia   +2 more
doaj   +1 more source

The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction

open access: yesPharmaceuticals, 2011
The endocannabinoid system (ECS) has been implicated in many physiological functions, including the regulation of appetite, food intake and energy balance, a crucial involvement in brain reward systems and a role in psychophysiological homeostasis ...
Francisco-Javier Bermúdez-Silva   +3 more
doaj   +1 more source

New Perspectives in the Studies on Endocannabinoid and Cannabis: A Role for the Endocannabinoid-Arachidonic Acid Pathway in Drug Reward and Long-Lasting Relapse to Drug Taking

open access: yesJournal of Pharmacological Sciences, 2004
Growing evidence on the involvement of cannabinoids in the rewarding effects of various kinds of drugs of abuse has suggested that not only the classical dopaminergic and opioidergic, but also the most recently established endocannabinoid system is ...
Tsuneyuki Yamamoto   +2 more
doaj   +1 more source

Role of Cannabinoids in the Regulation of Bone Remodelling

open access: yesFrontiers in Endocrinology, 2012
The endocannabinoid system plays a key role in regulating a variety of physiological processes such as appetite control and energy balance, pain perception, and immune responses. Recent studies have implicated the endocannabinoid system in the regulation
Aymen I Idris, Stuart H Ralston
doaj   +1 more source

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