Results 21 to 30 of about 54,731 (237)

Emerging mechanisms by which endocannabinoids and their derivatives modulate bacterial populations within the gut microbiome

Advances in Drug and Alcohol Research, 2023
Bioactive lipids such as endocannabinoids serve as important modulators of host health and disease through their effects on various host functions including central metabolism, gut physiology, and immunity.
Melissa Ellermann
doaj   +1 more source

Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex. [PDF]

PLoS ONE, 2007
Cannabinoids have deleterious effects on prefrontal cortex (PFC)-mediated functions and multiple evidences link the endogenous cannabinoid (endocannabinoid) system, cannabis use and schizophrenia, a disease in which PFC functions are altered. Nonetheless,
Mathieu Lafourcade, Izaskun Elezgarai, Susana Mato, Yamina Bakiri, Pedro Grandes, Olivier J Manzoni   +5 more
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Contribution of Endocannabinoids to Intrinsic Motivation for Undirected Singing in Adult Zebra Finches

Frontiers in Physiology, 2022
Songbirds, such as zebra finches, spontaneously produce many song renditions for vocal practice even in the absence of apparent recipients throughout their lives.
Yunbok Kim, Satoshi Kojima
doaj   +1 more source

Effects of parabolic flight and spaceflight on the endocannabinoid system in humans [PDF]

, 2012
The endocannabinoid system (ECS) plays an important role in the regulation of physiological functions, from stress and memory regulation to vegetative control and immunity.
Chouker, Alexander, Feuerecker, Matthias, Hauer, Daniela, Kaufmann, Ines, Morukov, Boris, Nichiporuk, Igor, Schelling, Gustav, Strewe, Claudia   +7 more
core   +1 more source

Oral Ultramicronized Palmitoylethanolamide: Plasma and Tissue Levels and Spinal Anti-hyperalgesic Effect

Frontiers in Pharmacology, 2018
Palmitoylethanolamide (PEA) is a pleiotropic lipid mediator with established anti-inflammatory and anti-hyperalgesic activity. Ultramicronized PEA (PEA-um) has superior oral efficacy compared to naïve (non-micronized) PEA.
Stefania Petrosino, Stefania Petrosino, Marika Cordaro, Roberta Verde, Aniello Schiano Moriello, Aniello Schiano Moriello, Gabriele Marcolongo, Carlo Schievano, Rosalba Siracusa, Fabiana Piscitelli, Alessio F. Peritore, Rosalia Crupi, Daniela Impellizzeri, Emanuela Esposito, Salvatore Cuzzocrea, Vincenzo Di Marzo   +15 more
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Enhanced Anandamide Plasma Levels in Patients with Complex Regional Pain Syndrome following Traumatic Injury: A Preliminary Report [PDF]

, 2009
The complex regional pain syndrome (CRPS) is a disabling neuropathic pain condition that may develop following injuries of the extremities. The pathogenesis of this syndrome is not clear; however, it includes complex interactions between the nervous and ...
Campolongo, P., Chouker, A., Hauer, D., Huge, V., Kaufmann, I., Schelling, G., Thiel, M., Vogeser, M.   +7 more
core   +1 more source

The therapeutic aspects of the endocannabinoid system (ECS) for cancer and their development: from nature to laboratory [PDF]

, 2016
The endocannabinoid system (ECS) is a group of neuromodulatory lipids and their receptors, which are widely distributed in mammalian tissues. ECS regulates various cardiovascular, nervous, and immune system functions inside cells.
Botta, Bruno, Czarnecka, Anna M., Khan, Mohammed I., Król, Magdalena, Sobocińska, Anna A., Szczylik, Cezary   +5 more
core   +1 more source

Genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP) and its association with Physiological mechanisms controlling Body Mass Index (BMI) [PDF]

, 2014
Taste sensitivity to the bitter compound 6-n-propylthiouracil (PROP) is considered a marker for individual differences in taste perception that may influence food preferences and eating behavior, and thereby energy metabolism.
Banni S, Crnjar R, Melis M, Tepper BJ, Tomassini Barbarossa I   +4 more
core   +1 more source

Differential Cannabinoid Receptor Expression during Reactive Gliosis: a Possible Implication for a Nonpsychotropic Neuroprotection

The Scientific World Journal, 2009
Activated microglia and astrocytes produce a large number of inflammatory and neurotoxic substances in various brain pathologies, above all during neurodegenerative disorders.
Daniele De Filippis, Antonio Steardo, Alessandra D'Amico, Caterina Scuderi, Mariateresa Cipriano, Giuseppe Esposito, Teresa Iuvone   +6 more
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Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier

Frontiers in Endocrinology, 2019
In states of intestinal dysbiosis, a perturbation of the normal microbiome composition, the intestinal epithelial barrier (IEB) permeability is increased as a result of the disruption of the epithelial tight junction protein network, in which occludin is
Lea Tunisi, Lea Tunisi, Nicola Forte, Alba Clara Fernández-Rilo, Isabella Mavaro, Isabella Mavaro, Raffaele Capasso, Livia D'Angelo, Livia D'Angelo, Nataša Milić, Luigia Cristino, Vincenzo Di Marzo, Vincenzo Di Marzo, Letizia Palomba, Letizia Palomba   +14 more
doaj   +1 more source