Results 11 to 20 of about 27,157 (201)

Endocannabinoids and Reproduction [PDF]

open access: yesInternational Journal of Endocrinology, 2014
Infertility is a worldwide reproductive health problem whose consequences have deep psychological and social impact in health, demographic change, and wellbeing. Thus, the knowledge of basic, conserved modulators of reproduction might contribute to the discovery of new potential target for the exploitation of drugs to treat infertility in humans ...
Rosaria Meccariello   +3 more
openaire   +4 more sources

Endocannabinoids and exercise [PDF]

open access: yesBritish Journal of Sports Medicine, 2004
Exercise induces changes in mental status, particularly analgesia, sedation, anxiolysis, and a sense of wellbeing. The mechanisms underlying these changes remain unknown. Recent findings show that exercise increases serum concentrations of endocannabinoids, suggesting a possible explanation for a number of these changes.
A, Dietrich, W F, McDaniel
openaire   +2 more sources

The Microbiome and Gut Endocannabinoid System in the Regulation of Stress Responses and Metabolism

open access: yesFrontiers in Cellular Neuroscience, 2022
The endocannabinoid system, with its receptors and ligands, is present in the gut epithelium and enteroendocrine cells, and is able to modulate brain functions, both indirectly through circulating gut-derived factors and directly through the vagus nerve,
Raj Kamal Srivastava   +3 more
doaj   +1 more source

Endocannabinoid Turnover [PDF]

open access: yes, 2017
In this review, we consider the biosynthetic, hydrolytic, and oxidative metabolism of the endocannabinoids anandamide and 2-arachidonoylglycerol. We describe the enzymes associated with these events and their characterization. We identify the inhibitor profile for these enzymes and the status of therapeutic exploitation, which to date has been limited ...
Fowler, Christopher J.   +2 more
openaire   +4 more sources

The Epigenetics of the Endocannabinoid System [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
The endocannabinoid system (ES) is a cell-signalling system widely distributed in biological tissues that includes endogenous ligands, receptors, and biosynthetic and hydrolysing machineries. The impairment of the ES has been associated to several pathological conditions like behavioural, neurological, or metabolic disorders and infertility, suggesting
Meccariello Rosaria   +6 more
openaire   +2 more sources

Emerging mechanisms by which endocannabinoids and their derivatives modulate bacterial populations within the gut microbiome

open access: yesAdvances in Drug and Alcohol Research, 2023
Bioactive lipids such as endocannabinoids serve as important modulators of host health and disease through their effects on various host functions including central metabolism, gut physiology, and immunity.
Melissa Ellermann
doaj   +1 more source

Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity

open access: yesJournal of Neuroinflammation, 2019
Background Palmitoylethanolamide (PEA) is a pleiotropic endogenous lipid mediator currently used as a “dietary food for special medical purposes” against neuropathic pain and neuro-inflammatory conditions.
Stefania Petrosino   +9 more
doaj   +1 more source

Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex. [PDF]

open access: yesPLoS ONE, 2007
Cannabinoids have deleterious effects on prefrontal cortex (PFC)-mediated functions and multiple evidences link the endogenous cannabinoid (endocannabinoid) system, cannabis use and schizophrenia, a disease in which PFC functions are altered. Nonetheless,
Mathieu Lafourcade   +5 more
doaj   +1 more source

Contribution of Endocannabinoids to Intrinsic Motivation for Undirected Singing in Adult Zebra Finches

open access: yesFrontiers in Physiology, 2022
Songbirds, such as zebra finches, spontaneously produce many song renditions for vocal practice even in the absence of apparent recipients throughout their lives.
Yunbok Kim, Satoshi Kojima
doaj   +1 more source

Metabolism of endocannabinoids

open access: yesPostępy Higieny i Medycyny Doświadczalnej, 2016
Endocannabinoids belong to a group of ester, ether and amide derivatives of fatty acids, which are endogenous ligands of receptors CB1, CB2, TRPV1 and GPR55 that are included in the endocannabinoid system of the animal organism. The best known endocannabinoids are: N-arachidonylethanolamide called anandamide (AEA) and 2-arachidonoylglycerol (2-AG ...
Michał, Biernacki   +1 more
openaire   +2 more sources

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