Results 31 to 40 of about 46,693 (214)

Multifunctional Framework Nucleic Acid Vehicle for Antibiotic Sensitization and Treatment of Methicillin‐Resistant Staphylococcus aureus

Aggregate, EarlyView.
A self‐assembling, aggregation‐enhanced tetrahedral DNA nanostructure (tFNA), termed TACs, enables localized accumulation and sustained release of ceftriaxone while co‐delivering antisense oligonucleotides that silence mecA, reduce PBP2a expression, and restore β‐lactam susceptibility in MRSA.
Yicheng Zhao, Jingyi Si, Shisong Jing, Bingmei Wang, Yueshan Xu, Jiyu Guan, Quan Liu, Jianlei Shen, Min Lv, Li Wang, Changfeng Zhu   +10 more
wiley   +1 more source

Treatment of Libman-Sacks endocarditis by combination of warfarin and immunosuppressive therapy

Türk Kardiyoloji Derneği Arşivi, 2019
Antiphospholipid syndrome (APS) is a clinical disorder that creates an increased risk of arterial or venous thrombotic events or pregnancy-associated complications and includes the presence of autoantibodies against negatively charged phospholipids. This
Mehmet Rasih Sonsöz, Rukiye Dilara Tekin, Ahmet Gül, Zehra Buğra, Dursun Atılgan   +4 more
doaj   +1 more source

Transport powered by bacterial turbulence [PDF]

Phys. Rev. Lett. 112, 158101 (2014), 2014
We demonstrate that collective turbulent-like motion in a bacterial bath can power and steer directed transport of mesoscopic carriers through the suspension. In our experiments and simulations, a microwedge-like "bulldozer" draws energy from a bacterial bath of varied density. We obtain that a maximal transport speed is achieved in the turbulent state
arxiv   +1 more source

Genomic Insights Into a Strong Biofilm‐Forming Enterococcus faecalis MTR_EFS01 Strain Isolated From a Shrimp in Bangladesh

Animal Research and One Health, EarlyView.
This study characterizes a multidrug‐resistant and strong biofilm‐forming Enterococcus faecalis strain obtained from a shrimp sample in Bangladesh. ABSTRACT Enterococcus faecalis is known for its ability to form strong biofilms and its role as an opportunistic pathogen. In this study, we screened and characterized a multidrug‐resistant (MDR) and strong
Md. Ashek Ullah, Md. Saiful Islam, Md. Liton Rana, Jayedul Hassan, Md. Tanvir Rahman   +4 more
wiley   +1 more source

Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants

Chemistry &Biodiversity, EarlyView.
The study workflow utilized validated in silico [molecular docking, fingerprinting, pharmacokinetics prediction, molecular dynamics (MD) simulation, ligand‐protein contact maps] tools to bioprospect a wide variety of metabolites surveyed from South African plants with antimicrobial activities, and target them against the key S.
Christiana Eleojo Aruwa, Saheed Sabiu
wiley   +1 more source

Acute myocardial infarction as the first sign of infective endocarditis: a case report

Journal of International Medical Research, 2020
Infective endocarditis is a bacterial or fungal infection of the heart valves or endocardial surface, and it frequently forms vegetation and can lead to systemic embolism.
Jian Zhao, Jing Yang, Wei Chen, Xiaomin Yang, Yaoting Liu, Xiaoliang Cong, Zhigang Huang, Na Li   +7 more
doaj   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

Imaging the emergence of bacterial turbulence: phase diagram and transition kinetics [PDF]

arXiv, 2020
We experimentally study the emergence of collective bacterial swimming, a phenomenon often referred to as bacterial turbulence. A phase diagram of the flow of 3D E. coli suspensions spanned by bacterial concentration, the swimming speed of bacteria and the number fraction of active swimmers is systematically mapped, which shows quantitative agreement ...
arxiv  

Rapid Diagnostic Testing for Infective Endocarditis and Myocarditis Using Nanopore Targeted Sequencing

iLABMED, EarlyView.
This research presents a method based on nanopore targeted sequencing (NTS) with pathogen‐specific panels for testing infective endocarditis (IE) and myocarditis. The NTS achieved a detection limit of 20 copies/test for the IE target panel and 10 copies/test for the myocarditis target panel.
Aisi Fu, Xian Wang, Zhiyong Shen, Jiashuang Gu, Ting Zhang, Feiyan Wang, Shiyu Jia, Linmei Yang, Feng Li, Jie Geng, Jun Cheng   +10 more
wiley   +1 more source

All‐in‐one optical microfiber with an interface for MRSA in biofilms: Integrating rapid quantitative analysis and synergistic antimicrobial therapy

InfoMat, EarlyView.
Aiming at the management of MRSA biofilms, an all‐in‐one optical microfiber that integrated rapid quantitative analysis with synergistic antimicrobial therapy is developed. The prepared interfacial‐functionalized optical microfiber demonstrates the ability to detect MRSA concentrations in infection sites, enhance therapeutic efficacy, and assess ...
Pengwei Chen, Haotian Wu, Lin Liang, Tao Hu, Yunyun Huang, Zhen Lin, Hao Wu, Bai‐Ou Guan   +7 more
wiley   +1 more source