Results 31 to 40 of about 48,874 (156)

Bartonella henselae infective endocarditis with dissemination: A case report and literature review in Southeast Asia

IDCases, 2018
Bartonella is among the most common causes of culture-negative infective endocarditis, with B. henselae being one of the most frequently reported species.
Preudtipong Noopetch, Teerada Ponpinit, Chusana Suankratay   +2 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Action of Betulinic Acid in the Inhibition of Efflux Pump NorA in Staphylococcus aureus Strains: In Vitro and In Silico Approaches

Chemistry &Biodiversity, EarlyView.
ABSTRACT Antibiotic resistance poses a serious challenge to public health, particularly in the case of Staphylococcus aureus, a Gram‐positive bacterium that employs multiple resistance mechanisms, including efflux pumps such as NorA, which extrude antimicrobial compounds from the cell and reduce antibiotic efficacy. Therefore, the search for substances
Camila Aparecida Pereira da Silva, Nara juliana Santos Araujo, Cícera Datiane Morais Oliveira‐Tintino, José Maria Barbosa Filho, Gabriel Gonçalves Alencar, José Bezerra de Araújo‐Neto, Josefa Sayonara dos Santos, Juliete Bezerra Soares, Carolina Bandeira Domiciano, Henrique Douglas Melo Coutinho, Jacqueline Cosmo Andrade‐Pinheiro   +10 more
wiley   +1 more source

Acute myocardial infarction as the first sign of infective endocarditis: a case report

Journal of International Medical Research, 2020
Infective endocarditis is a bacterial or fungal infection of the heart valves or endocardial surface, and it frequently forms vegetation and can lead to systemic embolism.
Jian Zhao, Jing Yang, Wei Chen, Xiaomin Yang, Yaoting Liu, Xiaoliang Cong, Zhigang Huang, Na Li   +7 more
doaj   +1 more source

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

Interdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan, Adnan Shakoor, Sadia Kanwal   +2 more
wiley   +1 more source

Treatment of Libman-Sacks endocarditis by combination of warfarin and immunosuppressive therapy

Türk Kardiyoloji Derneği Arşivi, 2019
Antiphospholipid syndrome (APS) is a clinical disorder that creates an increased risk of arterial or venous thrombotic events or pregnancy-associated complications and includes the presence of autoantibodies against negatively charged phospholipids. This
Mehmet Rasih Sonsöz, Rukiye Dilara Tekin, Ahmet Gül, Zehra Buğra, Dursun Atılgan   +4 more
doaj   +1 more source

Dose‐dependent association of systemic comorbidities with periodontitis severity: A large population cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background To examine whether the associations between periodontitis and multiple systemic conditions increase with increasing severity of periodontitis using a multi‐center electronic health record (EHR) repository. Methods A cross‐sectional analysis was conducted using EHR data from 9 dental schools in the United States.
Muhammad H. A. Saleh, Hamoun Sabri
wiley   +1 more source

Incidence and Outcomes of Brucella Endocarditis in a High-Prevalence Area: A Single-Center Study

Journal of Epidemiology and Global Health
Objective To analyze the clinical characteristics of Brucella endocarditis (BE) and observe the factors related to death to provide guidance for clinical treatment.
Shufang Pan, Yunyue Zhao, Kaixiang Zhou, Shuru Chen, Miriban Maimaitiming, Jing Wu, Maimaitiaili Tuerxun, Yutian Chong, Jianyun Zhu   +8 more
doaj   +1 more source

Reduced prevalence of periodontitis in antidepressant users: Findings from a large‐scale US sample

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis and major depression disorder have been shown to have a bidirectional association. However, the impact of antidepressants, the primary pharmacological treatment for depression, on periodontal health remains unclear.
María Martínez, David Fraguas, Elena Figuero, Francesco D´Aiuto   +3 more
wiley   +1 more source

Safety of Baricitinib for the Treatment of Atopic Dermatitis in Adults Over a Median of 1.6 and up to 4.6 Years Treatment: Final Integrated Analysis of Eight Clinical Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Baricitinib is a selective Janus kinase (JAK)1/JAK2 inhibitor approved in more than 70 countries for the treatment of moderate‐to‐severe atopic dermatitis (AD) in adults, and in over 30 countries for adolescents and children from age 2 years with moderate‐to‐severe AD, who are candidates for systemic therapy.
Antonio Costanzo, Antonio Torrelo, Eric L. Simpson, Marjolein De Bruin‐Weller, Diamant Thaçi, Norito Katoh, Silvia Sabatino, Andrew Buchanan, Kasia Morawska, Samuel Ogwu, Karen Denning, Jonathan I. Silverberg   +11 more
wiley   +1 more source