Results 61 to 70 of about 1,190,140 (229)

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

A Case Report of Chlamydia Psittaci Pneumonia and Pulmonary Aspergillosis Diagnosed by Nanopore Sequencing

iLABMED, EarlyView.
ABSTRACT This paper reports a case of Chlamydia psittaci pneumonia and pulmonary aspergillosis with concurrent liver injury. The patient was admitted to the hospital with coughing, expectoration, and fever for 5 days. Laboratory tests upon admission revealed abnormalities in liver function.
Chang Song, Chunyan Zhao, Aichun Huang, Chaoyan Xu, Chunmei Zeng, Qingdong Zhu   +5 more
wiley   +1 more source

All‐in‐one optical microfiber with an interface for MRSA in biofilms: Integrating rapid quantitative analysis and synergistic antimicrobial therapy

InfoMat, EarlyView.
Aiming at the management of MRSA biofilms, an all‐in‐one optical microfiber that integrated rapid quantitative analysis with synergistic antimicrobial therapy is developed. The prepared interfacial‐functionalized optical microfiber demonstrates the ability to detect MRSA concentrations in infection sites, enhance therapeutic efficacy, and assess ...
Pengwei Chen, Haotian Wu, Lin Liang, Tao Hu, Yunyun Huang, Zhen Lin, Hao Wu, Bai‐Ou Guan   +7 more
wiley   +1 more source

Aspergillus fumigatus endocarditis in a splenectomized patient with no risk factors

IDCases, 2020
Aspergillus endocarditis is a rare cause of culture-negative fungal endocarditis, after Candida endocarditis. Typical risk factors include intravenous drug use, immunosuppression, prior cardiac surgery or presence of prosthetic heart valves ...
Abhimanyu Aggarwal, Karen Hogan, Armando Paez   +2 more
doaj  

Assessment of Factors Contributing to Infection Severity and High Levels of Drug Resistance in Clinical Enterococcus Isolates

Journal of Clinical Laboratory Analysis, Volume 39, Issue 14, July 2025.
E. faecalis was the predominant species (60.7%). Moreover, 39.3% of the isolates were identified as VRE with an MIC > 32 μg/mL, and the vanA gene was detected in 35.7% of the isolates. High‐level resistance to gentamicin and streptomycin was observed in 60.7% and 50% of the isolates, respectively.
Maryam Koleini, Ahmad Mosadegh, Farzan Madadizadeh, Hamid Heidari   +3 more
wiley   +1 more source

A relapse of acute group B streptococcus meningitis in a healthy adult: Case report and review of the literatures

Journal of General and Family Medicine, EarlyView.
Abstract Streptococcus agalactiae (GBS) is a rare cause of meningitis in healthy adults. We report the case of a healthy 33‐year‐old man with acute GBS meningitis who experienced relapsed high‐grade fever and increased intracranial pressure following completing intravenous antibiotics.
Wannisa Wongpipathpong, Pornrujee Hirunpat, Suppachok Kirdlarp, Somnuek Sungkanuparph   +3 more
wiley   +1 more source

Vanquish the vancomycin trough: a real‐world experience of pharmacist‐driven Bayesian software‐guided dosing using area under the curve (AUC) targets

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background A tertiary healthcare institution, located in New Zealand, switched from targeting trough vancomycin concentrations to 24‐h area under the concentration‐time curve (AUC24), facilitated by pharmacists using a Bayesian software‐guided approach.
Duncan Yorkston, Marie‐Claire Morahan, Vicki Campbell, Nirvana Selagan, Karensa Houghton, Sharon Gardiner, Paul Chin   +6 more
wiley   +1 more source

Central line–associated bloodstream infections and complications in adult home parenteral nutrition: Observations from a quality improvement initiative

Nutrition in Clinical Practice, EarlyView.
Abstract The literature is inconsistent regarding differences in infection risk between central venous catheter types used for home parenteral nutrition (HPN). Our goal was to determine if significant differences exist in rates of infection and other complications between peripherally inserted central catheters, tunneled central venous catheters, and ...
Theresa A. Fessler, Mary B. Crandall, Sarah E. Schumacher, David N. Martin   +3 more
wiley   +1 more source

Lupeol as a Potential Inhibitor of NorA Efflux Pumps in Staphylococcus aureus: In Silico and In Vitro Evidence

ChemistryOpen, EarlyView.
Antimicrobial resistance remains one of the major challenges to global public health, compromising the effectiveness of treatments and contributing to increased morbidity and mortality associated with bacterial infections. Among the mechanisms involved, efflux pumps—such as NorA, expressed in resistant strains of Staphylococcus aureus—are particularly ...
Nara Juliana Santos Araújo, Camila Aparecida Pereira Silva, Vanessa Lima Bezerra, Cicera Datiane Morais Oliveira‐Tintino, Gabriel Gonçalves de Alencar, Maria do Socorro Costa, Ana Raquel Pereira da Silva, Josefa Sayonara dos Santos, Kamila Correa Camara, Heberty diTarso Fernandes Facundo, Lívia Pereira Ferreira, Henrique Douglas Melo Coutinho, José Maria Barbosa Filho, Carolina Bandeira Domiciano, José Bezerra de Araújo‐Neto, Jacqueline Cosmo Andrade‐Pinheiro.   +15 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source