Results 71 to 80 of about 1,251,414 (287)

Successful prophylaxis of experimental streptococcal endocarditis with single doses of sublethal concentrations of penicillin [PDF]

, 2017
Penicillin prophylaxis against experimental endocarditis due to a strain of Streptococcus intermedtus isolated from a patient with endocarditis was studied in rats.
Francioli, P., Glauser, M. P.
core  

The biofilm‐associated bacterial infections unrelated to indwelling devices

IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2020
Biofilms are microbial communities established in the self‐produced extracellular substances that include up to 80% of associated microbial infections.
Rasoul Mirzaei, Rokhsareh Mohammadzadeh, M. Alikhani, M. Shokri Moghadam, Sajad Karampoor, Sima Kazemi, Alireza Barfipoursalar, R. Yousefimashouf   +7 more
semanticscholar   +1 more source

Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature

British Journal of Clinical Pharmacology, EarlyView.
Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen, Daan J. Touw, Kim Klein, Gertjan J. L. Kaspers, Paola Mian   +4 more
wiley   +1 more source

Incidence and Outcomes of Brucella Endocarditis in a High-Prevalence Area: A Single-Center Study

Journal of Epidemiology and Global Health
Objective To analyze the clinical characteristics of Brucella endocarditis (BE) and observe the factors related to death to provide guidance for clinical treatment.
Shufang Pan, Yunyue Zhao, Kaixiang Zhou, Shuru Chen, Miriban Maimaitiming, Jing Wu, Maimaitiaili Tuerxun, Yutian Chong, Jianyun Zhu   +8 more
doaj   +1 more source

Bifidobacterium longum subsp. longum CCFM1375 Mitigates Chronic Kidney Disease Progression via Gut Microbiota Modulation and Gut Barrier Restoration

Food Frontiers, EarlyView.
(1) Bifidobacterium longum subsp. longum CCFM1375 restored gut barrier integrity by upregulating ZO‐1/ZO‐2 and suppressing IL‐6/TNF‐α, thereby reducing serum LPS and improving creatinine/BUN levels. (2) Reshaped gut microbiota: enriched beneficial species (Faecalibaculum rodentium, Asaccharobacter celatus, Adlercreutzia equolifaciens) while suppressing
Hongchao Wang, Xinchen Lv, Yue Zhang, Jinlin Zhu, Jia Hua, Bin Liu, Jianxin Zhao, Hao Zhang, Wei Chen, Wenwei Lu, Zhijian Zhang, Liang Wang   +11 more
wiley   +1 more source

Survival of Staphylococcus aureus ST398 in the human nose after artificial inoculation. [PDF]

, 2012
There is evidence that MRSA ST398 of animal origin is only capable of temporarily occupying the human nose, and it is therefore, often considered a poor human colonizer.We inoculated 16 healthy human volunteers with a mixture of the human MSSA strain ...
Advances in Veterinary Medicine, Dep Infectieziekten Immunologie, Lindsay, J.A., McCarthy, A.J., Slingerland, B.C.G.C., Snijders, S.V., Strategic Infection Biology, Tavakol, M., van Belkum, A., van Wamel, W.J., Verbrugh, H.A., Vos, M.C., Wagenaar, J.A.   +12 more
core   +5 more sources

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

Interdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan, Adnan Shakoor, Sadia Kanwal   +2 more
wiley   +1 more source

Surgical Options for Aortic Root Replacement in Destructive Endocarditis

Brazilian Journal of Cardiovascular Surgery
Objective: To analyze patients’ preoperative characteristics, surgical data, postoperative courses, and short- and long-term outcomes after implantation of different full-root prostheses for destructive aortic valve endocarditis.
Marcin Szczechowicz, Alexander Weymann, Sabreen Mkalaluh, Ahmed Mashhour, Konstantin Zhigalov, Jerry Easo   +5 more
doaj   +1 more source

Renal AA-amyloidosis in intravenous drug users - a role for HIV-infection? [PDF]

, 2012
Background: Chronic renal disease is a serious complication of long-term intravenous drug use (IVDU). Recent reports have postulated a changing pattern of underlying nephropathy over the last decades.
Amann, Kerstin Ute, Betz, Christoph, Bickel, Markus, Büttner, Maike, Grützmacher, Peter, Haack, Hans Stefan, Jung, Oliver, Stephan, Christoph   +7 more
core   +2 more sources

Dose‐dependent association of systemic comorbidities with periodontitis severity: A large population cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background To examine whether the associations between periodontitis and multiple systemic conditions increase with increasing severity of periodontitis using a multi‐center electronic health record (EHR) repository. Methods A cross‐sectional analysis was conducted using EHR data from 9 dental schools in the United States.
Muhammad H. A. Saleh, Hamoun Sabri
wiley   +1 more source