Results 71 to 80 of about 25,313 (227)

Virtual left atrial appendage occlusion in paroxysmal atrial fibrillation during sinus rhythm predicts variable reductions in blood stasis

The Journal of Physiology, EarlyView.
Abstract figure legend Stasis before and after left atrial appendage occlusion (LAAO) in participants with high stasis and low stasis. Stasis is predominantly located in LAA and reduced after LAAO. But in the participant with high stasis, stasis remains close to the occlusion site, indicating a potential risk for device related thrombi.
Sophia Bäck, Jonas Lantz, Iulia Skoda, Lars O. Karlsson, Anders Persson, Carl‐Johan Carlhäll, Tino Ebbers   +6 more
wiley   +1 more source

Unveiling sex dimorphism in the healthy cardiac anatomy: Fundamental differences between male and female heart shapes

The Journal of Physiology, EarlyView.
Abstract figure legend We present a shape modelling‐based morphological analysis of sex differences in cardiac anatomy. We conduct our analysis on 456 healthy subjects from the UK Biobank (227M/229F) to uncover sex‐based differences in healthy cardiac morphology.
Beatrice Moscoloni, Cameron Beeche, Julio A. Chirinos, Patrick Segers, Mathias Peirlinck   +4 more
wiley   +1 more source

Effect of myocardial heterogeneity on ventricular electro-mechanical responses: a computational study

BioMedical Engineering OnLine, 2019
Background The heart wall exhibits three layers of different thicknesses: the outer epicardium, mid-myocardium, and inner endocardium. Among these layers, the mid-myocardium is typically the thickest.
Nida Dusturia, Seong Wook Choi, Kwang Soup Song, Ki Moo Lim   +3 more
doaj   +1 more source

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

The Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach, Laura Bevis, Cynthia Nwanna, Alexander M Zolotarev, Mahmoud Ehnesh, Semhar Biniam Misghina, Sayed Al‐Aidarous, Shohreh Honarbakhsh, Caroline H. Roney   +8 more
wiley   +1 more source

In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging‐based fibrotic left ventricle models

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero, Jairo Rodríguez Padilla, Nicolas Cedilnik, Buntheng Ly, Juan F. Gomez, Maxime Sermesant, Mihaela Pop, Beatriz Trenor   +7 more
wiley   +1 more source

Mesoscopic anatomy and histotopography of the left atrial appendage walls in human fetal heart

Сибирский научный медицинский журнал
Normal anatomy of the left atrial appendage (LAA) of human fetus is of a great importance for fetal cardiac surgery and heart bioprinting. Aim of the study was to clarify the mesoscopic anatomy and histotopography of different parts of the LAA walls in ...
A. A. Gaponov, I. D. Ufimtseva, E. G. Dmitrieva, D. K. Kuznetsov, V. I. Pryakhina, A. A. Iakimov   +5 more
doaj   +1 more source

Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions

Nature Communications, 2019
It is unknown how endocardium growth is coordinated with that of the myocardium in the zebrafish. Here, the authors show that myocardial chamber volume expansion causes increased endocardial tissue tension, which in turn triggers Hippo signaling-mediated
Dorothee Bornhorst, Peng Xia, Hiroyuki Nakajima, Chaitanya Dingare, Wiebke Herzog, Virginie Lecaudey, Naoki Mochizuki, Carl-Philipp Heisenberg, Deborah Yelon, Salim Abdelilah-Seyfried   +9 more
doaj   +1 more source

Ectopic Noggin in a Population of Nfatc1 Lineage Endocardial Progenitors Induces Embryonic Lethality

Journal of Cardiovascular Development and Disease, 2014
The initial heart is composed of a myocardial tube lined by endocardial cells. The TGFβ superfamily is known to play an important role, as BMPs from the myocardium signal to the overlying endocardium to create an environment for EMT.
Paige Snider, Olga Simmons, Jian Wang, Chinh Q. Hoang, Simon J. Conway   +4 more
doaj   +1 more source

4D ultrasound reveals regional left atrial strain remodelling in a murine model of reversible pressure overload

The Journal of Physiology, EarlyView.
Abstract figure legend Traditional planar imaging approaches of the left atrium do not capture complex geometry. Four‐dimensional imaging allows the acquisition of 3D data + time to visualize left atrial geometry and kinematics. We designed an advanced analysis technique to investigate left atrial biomechanics in a model of pressure overload and ...
John P. Salvas, Thomas Moore‐Morris, Craig J. Goergen, Pierre Sicard   +3 more
wiley   +1 more source

The Effect of Voxel Volume and Voxel Shape on Cardiac Diffusion Tensor Imaging Metrics

Magnetic Resonance in Medicine, Volume 95, Issue 4, Page 2063-2077, April 2026.
ABSTRACT Purpose Cardiac diffusion tensor imaging (cDTI) is signal‐to‐noise ratio (SNR)‐limited due to diffusion signal attenuation, long echo times from gradient moment nulling, and moderate myocardial T 2$$ {}_2 $$. Increasing voxel volume improves SNR but reduces spatial sensitivity and introduces physiological bias.
Ariel J. Hannum, Tyler E. Cork, Kawin Setsompop, Daniel B. Ennis   +3 more
wiley   +1 more source