Results 61 to 70 of about 25,805 (234)

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira   +3 more
wiley   +1 more source

Air embolism secondary to suspected lymphatic tissue disruption with severe exercise‐induced pulmonary haemorrhage

open access: yesEquine Veterinary Education, EarlyView.
Summary Air embolism is rare in horses and typically associated with complications following intravenous catheterisation or other medical procedures. Exercise‐induced pulmonary haemorrhage (EIPH) is common in racehorses but not usually associated with air embolism. This report describes a case of air embolism in a 4‐year‐old Thoroughbred with EIPH. The
J. Wittenberg   +7 more
wiley   +1 more source

Impact of Dental Status on Heart Transplantation Outcomes

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Oral infections and poor dental health may contribute to systemic complications after heart transplantation, yet data on their impact is limited. In the absence of standardized dental guidelines for transplant candidates, this study evaluated preoperative dental status and its association with post‐transplant outcomes.
Katharina Theresa Obermeier   +8 more
wiley   +1 more source

Epigenetics and Mechanobiology in Heart Development and Congenital Heart Disease

open access: yesDiseases, 2019
Congenital heart disease (CHD) is the most common birth defect worldwide and the number one killer of live-born infants in the United States. Heart development occurs early in embryogenesis and involves complex interactions between multiple cell ...
Dillon K. Jarrell   +2 more
doaj   +1 more source

Modified Anatomical Ablation Strategy for Mitral Isthmus

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Durable mitral isthmus (MI) block remains challenging in persistent atrial fibrillation (AF) ablation. Ethanol infusion into the vein of Marshall (EI‐VOM) enhances efficacy, but the minimal endocardial ablation extent post‐EI‐VOM is undefined.
Kui He   +7 more
wiley   +1 more source

Interplay of Probe Stability and Oscillation During Very‐High‐Power Short‐Duration Ablation in Pulmonary Vein Isolation for Atrial Fibrillation

open access: yesPacing and Clinical Electrophysiology, EarlyView.
This graphical abstract presents a comprehensive analysis of probe stability and oscillation during very high‐power short‐duration (vHPSD) pulmonary vein isolation (PVI) for atrial fibrillation. The findings indicate that oscillation velocity serves as a more reliable predictor of impedance drop and temperature changes than contact force alone ...
Ernesto Cristiano   +7 more
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

Hand2 Is an Essential Regulator for Two Notch-Dependent Functions within the Embryonic Endocardium

open access: yesCell Reports, 2014
The basic-helix-loop-helix (bHLH) transcription factor Hand2 plays critical roles during cardiac morphogenesis via expression and function within myocardial, neural crest, and epicardial cell populations.
Nathan J. VanDusen   +11 more
doaj   +1 more source

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