Results 51 to 60 of about 643,284 (202)

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Interferentes endócrinos no ambiente Endocrine disruptors in the enviroment

Química Nova, 2007
Although the hypothesis that environmental chemicals may exhibit endocrine disrupting effects is not new, the issue has been a growing level of concern due to reports of increased incidences of endocrine-related disease in humans, including declining ...
Gislaine Ghiselli, Wilson F. Jardim
doaj   +1 more source

Endocrine disrupting potential of replacement flame retardants – Review of current knowledge for nuclear receptors associated with reproductive outcomes

Environment International, 2021
Background and aim: Endocrine disrupting chemicals (EDCs) constitute a major public health concern because they can induce a large spectrum of adverse effects by interfering with the hormonal system.
Lola Bajard, Chander K. Negi, Vicente Mustieles, Lisa Melymuk, Stéphane Jomini, Johanna Barthelemy-Berneron, Mariana F. Fernandez, Ludek Blaha   +7 more
doaj   +1 more source

Machine‐Learning‐Assisted Impedance Component Analysis Enables Standardizable Surface Protein Analysis of Extracellular Vesicles Using Engineered Nanovesicles

Advanced Science, EarlyView.
This study establishes a universally applicable framework for vesicle surface analysis by combining engineered amyloid‐β‐displaying nanovesicles with machine‐learning‐optimized impedance spectroscopy. Equivalent‐circuit modeling reveals that membrane capacitance correlates with the surface protein states, enabling label‐free quantification of vesicle ...
Jaeyoon Song, Neethu Ramakrishnan, Sehyeon Kim, Huiseop Lee, Youngeun Kwon, Jinsik Kim   +5 more
wiley   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Exposure to Endocrine-Disrupting Chemicals and Early Onset of Menarche: A Systematic Review

Pollutants
There has been a decline in the age at which girls experience menarche worldwide. Research suggests that exposure to endocrine-disrupting chemicals is linked to negative health consequences, including early onset of menarche.
Anuli Njoku, Mousa Al-Hassan, Sharaban Tohura, Kaleigh Albert, Taryn Pierce, Wendemi Sawadogo   +5 more
doaj   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Assessing the risks of endocrine-disrupting chemicals

, 2009
In this chapter, four European regulatory frameworks are compared concerning how they cope with identifying and risk assessing endocrine-disrupting chemicals.
A. Beronius, A. Hanberg, Håkansson, H., J. Garai, Ruden, C, Garai, J, Garai, J., H. Håkansson, Hakansson, H, Hanberg, A., Hanberg, A,, C. Rudén, Rudén, Christina,, Beronius, A., Beronius, A,   +14 more
core   +1 more source

Effects of Endocrine-Disrupting Chemicals on Obesity and Diabetes

Endocrinology Research and Practice, 2023
The increasing incidence of obesity and type 2 diabetes mellitus (T2DM) is a global problem. Although the obesity epidemic is mostly associated with a lack of physical activity and diet, several chemicals have been demonstrated to have a potential role ...
Soner Caner, İlhan Yetkin
doaj  

Endocrine‐disrupting chemicals and male reproductive health

Reproductive Medicine and Biology, 2020
Background A number of different types of endocrine‐disrupting chemicals (EDCs) including bisphenol A, phthalates, pesticides, and other environmental chemicals have been shown to adversely impact upon male reproductive health.
Aditi Sharma, Josephine Mollier, Richard W. K. Brocklesby, Charlotte Caves, Channa N. Jayasena, Suks Minhas   +5 more
doaj   +1 more source