Results 231 to 240 of about 991,500 (305)

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Response to "Eleutheroembryo-based new approach methodologies for endocrine and metabolic endpoints: a comment on Christou et al. (2026)". [PDF]

NAM J
Christou M, Georgantzopoulou A, Hultman M, Song Y, Wennberg AC, Mentzel S, Embry M, Ott A, Suzuki T, Grassi G, Roush K, Lillicrap A.   +11 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Hormonal metabolic burden in diabetic retinopathy: the diabetic retina as an endocrine-responsive target organ. [PDF]

Front Endocrinol (Lausanne)
Chen J, Zhang L.
europepmc   +1 more source

Direct ultrastructural validation of endocrine cell identity in zebrafish pancreatic islets. [PDF]

Cell Tissue Res
Schmitner N, Deseife C, Neumann A, Salvenmoser W, Seybold AC, Kimmel RA, Meyer D.   +6 more
europepmc   +1 more source

Occupational cadmium exposure and endocrine biomarker alterations in male workers: a cross-sectional study. [PDF]

BMC Endocr Disord
Özkan Vardar D, Tutkun L, İritaş SB, Gözükara MG, Abuşoğlu G, Deniz S, Türksoy VA, Tutkun E.   +7 more
europepmc   +1 more source