Results 21 to 30 of about 653,779 (296)

25(OH)VitD and human endocrine and functional fertility parameters in women undergoing IVF/ICSI

Frontiers in Endocrinology, 2022
BackgroundVitamin D plays an important role in reproduction. Evidence shown that free 25-hydroxyvitamin D (25(OH)VitD) was more accurate than total 25(OH)VitD in reflecting the status of 25(OH)VitD during pregnancy. However, the relationship between free
Mei Tian, Suimin Zeng, Sufen Cai, Sufen Cai, Christoph Reichetzeder, Xiaoli Zhang, Xiaoli Zhang, Chenjun Yin, Weihong Kuang, Kexin Cheng, Yao Jiang, Mingqiu Tao, Yuan Zeng, Ge Lin, Ge Lin, Ge Lin, Jian Li, Fei Gong, Fei Gong, Fei Gong, Berthold Hocher, Berthold Hocher, Berthold Hocher, Berthold Hocher   +23 more
doaj   +1 more source

Endocrine Disorders and Genital Infections Impair Gynecological Health in APECED (APS-1)

Frontiers in Endocrinology, 2021
ObjectiveIn autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) defects in the autoimmune regulator gene lead to impaired immunotolerance.
Viivi Saari, Viivi Saari, Saila Laakso, Saila Laakso, Saila Laakso, Aila Tiitinen, Outi Mäkitie, Outi Mäkitie, Outi Mäkitie, Outi Mäkitie, Elina Holopainen, Elina Holopainen   +11 more
doaj   +1 more source

Point-of-use sweat biosensor to track the endocrine–inflammation relationship for chronic disease monitoring

Future Science OA, 2021
Aim: The hypothalamic–pituitary–adrenal axis is involved in maintaining homeostasis by engaging with the parasympathetic nervous system. During the process of disease affliction, this relationship is disturbed and there is an imbalance driven response ...
Sayali Upasham, Ashlesha Bhide, Kai-Chun Lin, Shalini Prasad   +3 more
doaj   +1 more source

Morphometric Analysis of Fetal Pancreas

MRIMS Journal of Health Sciences, 2016
Background: Pancreas is an important organ and it is the target of major diseases like pancreatitis, diabetes mellitus, exocrine pancreatic insufficiency, cystic fibrosis, pseudo-cysts, annular pancreas, neoplasm etc.
B Immanuel Navin Kumar, T Krupa Sailaja, T K Rajasree, S Sreelatha, G R Raveena Paul   +4 more
doaj   +1 more source

Selective proteasome degradation of C‐terminally‐truncated human WFS1 in pancreatic beta cells

FEBS Open Bio, 2023
Wolfram syndrome is a monogenic disease mainly caused by mutations in the WFS1 gene. Mutations in the WFS1 gene give rise to diabetes. Here, we characterized mutant WFS1 proteins by studying the stability of full‐length wild‐type (WT) WFS1, a missense ...
Hiraku Tokuma, Daisuke Sakano, Katsuya Tanabe, Yukio Tanizawa, Nobuaki Shiraki, Shoen Kume   +5 more
doaj   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source