Results 31 to 40 of about 1,101,401 (313)

The Impact of Endocrine Disruptors on Endocrine Targets

Hormone and Metabolic Research, 2010
Endocrine disruption represents one of the most controversial environmental issues of our époque. So far, many substances, both natural and artificial, have been recognized to interfere with endocrine signaling pathways. In intact laboratory animals, this interaction has been documented to generate adverse health outcomes by impairing normal functions.
Diamanti-Kandarakis, E., Palioura, E., Kandarakis, S. A., Koutsilieris, M.   +3 more
openaire   +3 more sources

Growth Hormone/Insulin Growth Factor Axis in Sex Steroid Associated Disorders and Related Cancers

Frontiers in Cell and Developmental Biology, 2021
To date, almost all solid malignancies have implicated insulin-like growth factor (IGF) signalling as a driver of tumour growth. However, the remarkable level of crosstalk between sex hormones, the IGF-1 receptor (IGF-1R) and its ligands IGF-1 and 2 in ...
Rachel Bleach, Mark Sherlock, Michael W. O’Reilly, Marie McIlroy   +3 more
doaj   +1 more source

Screening of endocrine organ-specific humoral autoimmunity in 47,XXY Klinefelter's syndrome reveals a significant increase in diabetes-specific immunoreactivity in comparison with healthy control men. [PDF]

, 2015
The aim of this study was to evaluate the frequency of humoral endocrine organ-specific autoimmunity in 47,XXY Klinefelter’s syndrome (KS) by investigating the autoantibody profile specific to type 1 diabetes (T1DM), Addison’s disease (AD), Hashimoto ...
ANZUINI, Antonella, GIANFRILLI, DANIELE, GRANATO, SIMONA, LENZI, Andrea, PANIMOLLE, FRANCESCA, RADICIONI, Antonio, Semeraro, A, TIBERTI, Claudio   +7 more
core   +1 more source

DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation [PDF]

, 2015
The acquisition of endocrine therapy resistance in estrogen receptor a (ERa) breast cancer patients represents a major clinical problem. Notch signalling has been extensively linked to breast cancer especially in patients who fail to respond to endocrine
Aifantis, Apatira, Apweiler, Brennan, Carroll, Chazotte, Chen, Coombes, Darbre, Eikesdal, Forgac, Goloubeva, Gul, Hill, Ho, Joffe, Johnston, Jones, Jones, Jones, Kane, Kang, Kocak, Lake, Le Borgne, Lendahl, Liu, Lupien, Mader, Mao, Martinez, McPherson, Medici, Meyer, Miele, Miele, Miele, Miyamoto, Nguyen, Nicolson, Roegiers, Sarkar, Schiff, Schilling, Schupbach, Sutherland, Taylor, Urbe, Vaccari, Venkanteshan, Wang, Webster, Wieczorek, Wong, Zahler   +54 more
core   +3 more sources

Hypothalamus-Pituitary Dysfunction as an Independent Risk Factor for Postoperative Central Nervous System Infections in Patients With Sellar Region Tumors

Frontiers in Endocrinology, 2021
ObjectiveThe purpose of this study was to verify that hypothalamus-pituitary dysfunction is one of the risk factors for postoperative central nervous system infections (PCNSIs).MethodWe performed a retrospective analysis of all patients with sellar ...
Junxian Wen, Rui Yin, Yihao Chen, Jianbo Chang, Baitao Ma, Wei Zuo, Xiao Zhang, Xiaojun Ma, Ming Feng, Renzhi Wang, Wenbin Ma, Junji Wei   +11 more
doaj   +1 more source

25(OH)VitD and human endocrine and functional fertility parameters in women undergoing IVF/ICSI

Frontiers in Endocrinology, 2022
BackgroundVitamin D plays an important role in reproduction. Evidence shown that free 25-hydroxyvitamin D (25(OH)VitD) was more accurate than total 25(OH)VitD in reflecting the status of 25(OH)VitD during pregnancy. However, the relationship between free
Mei Tian, Suimin Zeng, Sufen Cai, Sufen Cai, Christoph Reichetzeder, Xiaoli Zhang, Xiaoli Zhang, Chenjun Yin, Weihong Kuang, Kexin Cheng, Yao Jiang, Mingqiu Tao, Yuan Zeng, Ge Lin, Ge Lin, Ge Lin, Jian Li, Fei Gong, Fei Gong, Fei Gong, Berthold Hocher, Berthold Hocher, Berthold Hocher, Berthold Hocher   +23 more
doaj   +1 more source

Expression of the neural cell adhesion NCAM in endocrine cells of the ovary [PDF]

, 1991
In the adult mammalian ovary morphogenesis and differentiation processes are under hormonal control and, thus, occur in a highly regulated way during the sexual cycle.
Gratzl, Manfred, Lahr, G., Mayerhofer, Artur   +2 more
core   +1 more source

Cellular distribution and amount of chromogranin A in bovine endocrine pancreas [PDF]

, 1988
We determined the cellular distribution and the amount of chromogranin A in endocrine cells of bovine pancreas using a polyclonal antibody against bovine adrenomedullary chromogranin A. The relative amounts of chromogranin A in the different cells of the
Ehrhart, M., Gratzl, Manfred, Grube, D., Jörns, A.   +3 more
core   +1 more source

Endocrine Disorders and Genital Infections Impair Gynecological Health in APECED (APS-1)

Frontiers in Endocrinology, 2021
ObjectiveIn autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) defects in the autoimmune regulator gene lead to impaired immunotolerance.
Viivi Saari, Viivi Saari, Saila Laakso, Saila Laakso, Saila Laakso, Aila Tiitinen, Outi Mäkitie, Outi Mäkitie, Outi Mäkitie, Outi Mäkitie, Elina Holopainen, Elina Holopainen   +11 more
doaj   +1 more source

Point-of-use sweat biosensor to track the endocrine–inflammation relationship for chronic disease monitoring

Future Science OA, 2021
Aim: The hypothalamic–pituitary–adrenal axis is involved in maintaining homeostasis by engaging with the parasympathetic nervous system. During the process of disease affliction, this relationship is disturbed and there is an imbalance driven response ...
Sayali Upasham, Ashlesha Bhide, Kai-Chun Lin, Shalini Prasad   +3 more
doaj   +1 more source