Results 51 to 60 of about 858,546 (315)

Sirtuin 1 and Hormonal Regulations in Aging

Applied Sciences
Aging affects the structure and functions of all organs and systems in the organism. In the elderly, significant changes in hormonal levels are observed.
Milena Keremidarska-Markova, Iliyana Sazdova, Mitko Mladenov, Bissera Pilicheva, Plamen Zagorchev, Hristo Gagov   +5 more
doaj   +1 more source

Individual variation in the cortisol response to a simulated Olympic weightlifting competition is related to changes in future competitive performance

Biology of Sport, 2019
The cortisol (C) and testosterone (T) responses to experimental stress have been linked to sport and health outcomes several days to years later. Here we examined the utility of these biomarkers, taken across a simulated Olympic weightlifting (OWL ...
Blair T Crewther, Christian Cook, Joanna Orysiak, Piotr Zmijewski, Zbigniew Obmiński   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Hypothalamic-Pituitary and Other Endocrine Surveillance Among Childhood Cancer Survivors.

, 2021
Endocrine disorders in survivors of childhood, adolescent, and young adult (CAYA) cancers are associated with substantial adverse physical and psychosocial effects.
Yuen, Kevin C J, Mulder, Renee L., Packer, Roger J, Thompson, Joel, Hudson, Melissa M, Kremer, Leontien C. M., Cohen, Laurie E., Schouten-van Meeteren, Antoinette Y N, Hoving, Eelco W, Chemaitilly, Wassim, van Vuurden, Dannis, Neggers, Sebastian J.C.M.M.; id_orcid, Wallace, W Hamish, Constine, Louis S, van Santen, Hanneke M, Kremer, Leontien C.M., Denzer, Christian, Wallace, W. Hamish, Yuen, Kevin C. J., Kiserud, Cecilie E, Srivastava, Deokumar, Di Iorgi, Natascia, Neggers, Sebastian J. C. M. M., Thomas-Teinturier, Cécile, Constine, Louis S., Schouten-van Meeteren, Antoinette Y.N., Murray, Robert D., Mulder, Renee L, Raman, Sripriya, Sugden, Elaine, Murray, Robert D, Spoudeas, Helen A., Follin, Cecilia, Toogood, Andrew A., Gleeson, Helena, Neggers, Sebastian J C M M, Neggers, Sebastian J.C.M.M., van Santen, Hanneke M., Hudson, Melissa M., Torno, Lilibeth, Janssens, Geert O., Morsellino, Vera, Scheinemann, Katrin, Clement, Sarah C., Janssens, Geert O, Skinner, Roderick, Stades, Aline M, Kiserud, Cecilie E., Yuen, Kevin C.J., Thomas-Teinturier, C. cile, Spoudeas, Helen A, Armstrong, Gregory T., Schouten-van Meeteren, Antoinette Y. N., Cohen, Laurie E, Patterson, Briana, Hoving, Eelco W., Kremer, Leontien C M, Meacham, Lillian R., Fernandez, Alberto, Meacham, Lillian R, Packer, Roger J., Mostoufi-Moab, Sogol, Sommer, Grit, Clement, Sarah C, Bardi, Edit, Stades, Aline M., van Iersel, Laura, Toogood, Andrew A, Armstrong, Gregory T   +68 more
core   +1 more source

Diabetes Mellitus in Non-Functioning Adrenal Incidentalomas: Analysis of the Mild Autonomous Cortisol Secretion (MACS) Impact on Glucose Profile

Biomedicines
Non-functioning adrenal incidentalomas (NFAIs) have been placed in relationship with a higher risk of glucose profile anomalies, while the full-blown typical picture of Cushing’s syndrome (CS) and associated secondary (glucocorticoid-induced) diabetes ...
Alexandra-Ioana Trandafir, Adina Ghemigian, Mihai-Lucian Ciobica, Claudiu Nistor, Maria-Magdalena Gurzun, Tiberiu Vasile Ioan Nistor, Eugenia Petrova, Mara Carsote   +7 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

The endocrines in otology [PDF]

The Laryngoscope, 1921
n ...
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source