Results 1 to 10 of about 567,934 (192)

Relationship of Para and Perirenal Fat and High-Density Lipoprotein and Its Function in Patients with Type 2 Diabetes Mellitus

International Journal of Endocrinology, 2021
Background. Para and perirenal fat is a fat pad surrounding the kidneys. Recent studies showed the association between para and perirenal fat and cardiovascular diseases including atherosclerosis and hypertension.
Jing Ke, Yan Wang, Simo Liu, Kun Li, YueChao Xu, Longyan Yang, Dong Zhao   +6 more
doaj   +1 more source

Age-specific prevalence, subtypes and risk factors of metabolic diseases in Chinese adults and the different patterns from other racial/ethnic populations

BMC Public Health, 2022
Background Age has substantial influence on metabolic diseases patterns. Ethnic disparities of metabolic characteristics between Chinese and other populations also exist. Large-scale investigations of age-specific prevalence, subtypes and modifiable risk
Qiuyu Cao, Ruizhi Zheng, Ruixin He, Tiange Wang, Min Xu, Jieli Lu, Meng Dai, Di Zhang, Yuhong Chen, Zhiyun Zhao, Shuangyuan Wang, Hong Lin, Weiqing Wang, Guang Ning, Yufang Bi, Yu Xu, Mian Li   +16 more
doaj   +1 more source

Fat mass to fat-free mass ratio and the risk of non-alcoholic fatty liver disease and fibrosis in non-obese and obese individuals

Nutrition & Metabolism, 2021
Context Body composition may explain partially why non-obese individuals still at the risk of developing non-alcoholic fatty liver disease (NAFLD).
Huajie Dai, Jiali Xiang, Yanan Hou, Liping Xuan, Tiange Wang, Mian Li, Zhiyun Zhao, Yu Xu, Jieli Lu, Yuhong Chen, Weiqing Wang, Guang Ning, Yufang Bi, Min Xu   +13 more
doaj   +1 more source

Age-specific difference in the association between prediabetes and subclinical atherosclerosis: an analysis of a chinese prospective cohort study

Cardiovascular Diabetology, 2022
Background Prediabetes is an important risk factor of cardiovascular disease (CVD) and is associated with subclinical atherosclerosis. However, the evidence of prediabetes as a cardiovascular risk factor is mainly derived from middle-aged adults ...
Qiuyu Cao, Zhuojun Xin, Ruixin He, Tiange Wang, Min Xu, Jieli Lu, Meng Dai, Di Zhang, Yuhong Chen, Zhiyun Zhao, Shuangyuan Wang, Hong Lin, Weiqing Wang, Guang Ning, Yufang Bi, Yu Xu, Mian Li   +16 more
doaj   +1 more source

Dissecting Causal Relationships Between Gut Microbiota, Blood Metabolites, and Stroke: A Mendelian Randomization Study [PDF]

Journal of Stroke, 2023
Background and Purpose We investigated the causal relationships between the gut microbiota (GM), stroke, and potential metabolite mediators using Mendelian randomization (MR).
Qi Wang, Huajie Dai, Tianzhichao Hou, Yanan Hou, Tiange Wang, Hong Lin, Zhiyun Zhao, Mian Li, Ruizhi Zheng, Shuangyuan Wang, Jieli Lu, Yu Xu, Ruixin Liu, Guang Ning, Weiqing Wang, Yufang Bi, Jie Zheng, Min Xu   +17 more
doaj   +1 more source

Associations of body shapes with insulin resistance and cardiometabolic risk in middle-aged and elderly Chinese

Nutrition & Metabolism, 2021
Background We aimed to define refined body shapes by using multiple anthropometric traits that represent fat distribution, and evaluate their associations with risk of insulin resistance (IR) and cardiometabolic disorders in a Chinese population. Methods
Yulin Zhou, Yanan Hou, Jiali Xiang, Huajie Dai, Mian Li, Tiange Wang, Shuangyuan Wang, Hong Lin, Jieli Lu, Yu Xu, Yuhong Chen, Weiqing Wang, Yufang Bi, Min Xu, Zhiyun Zhao   +14 more
doaj   +1 more source

Opposite causal effects of birthweight on myocardial infarction and atrial fibrillation and the distinct mediating pathways: a Mendelian randomization study

Cardiovascular Diabetology, 2023
Background Previous observational studies have documented an inverse association of birthweight with myocardial infarction (MI) but a positive association with atrial fibrillation (AF).
Lijie Kong, Yiying Wang, Chaojie Ye, Chun Dou, Dong Liu, Min Xu, Jie Zheng, Ruizhi Zheng, Yu Xu, Mian Li, Zhiyun Zhao, Jieli Lu, Yuhong Chen, Weiqing Wang, Ruixin Liu, Yufang Bi, Tiange Wang, Guang Ning   +17 more
doaj   +1 more source

Stronger association of triglyceride glucose index than the HOMA-IR with arterial stiffness in patients with type 2 diabetes: a real-world single-centre study

Cardiovascular Diabetology, 2021
Background The triglyceride-glucose index (TyG index) has been proposed as a simple and reliable alternative insulin resistance (IR) marker, while the homeostasis model assessment for IR (HOMA-IR) is the most frequently used index.
Shujie Wang, Juan Shi, Ying Peng, Qianhua Fang, Qian Mu, Weiqiong Gu, Jie Hong, Yifei Zhang, Weiqing Wang   +8 more
doaj   +1 more source

Roles of gut microbiota in atrial fibrillation: insights from Mendelian randomization analysis and genetic data from over 430,000 cohort study participants

Cardiovascular Diabetology, 2023
Background Gut microbiota imbalances have been suggested as a contributing factor to atrial fibrillation (AF), but the causal relationship is not fully understood.
Huajie Dai, Tianzhichao Hou, Qi Wang, Yanan Hou, Zheng Zhu, Yijie Zhu, Zhiyun Zhao, Mian Li, Hong Lin, Shuangyuan Wang, Ruizhi Zheng, Yu Xu, Jieli Lu, Tiange Wang, Guang Ning, Weiqing Wang, Jie Zheng, Yufang Bi, Min Xu   +18 more
doaj   +1 more source

CBP/p300 HAT maintains the gene network critical for β cell identity and functional maturity

Cell Death and Disease, 2021
Loss of β cell identity and functional immaturity are thought to be involved in β cell failure in type 2 diabetes. CREB-binding protein (CBP) and its paralogue p300 act as multifunctional transcriptional co-activators and histone acetyltransferases (HAT)
Linlin Zhang, Chunxiang Sheng, Feiye Zhou, Kecheng Zhu, Shushu Wang, Qianqian Liu, Miaomiao Yuan, Zhaoqian Xu, Yun Liu, Jieli Lu, Jianmin Liu, Libin Zhou, Xiao Wang   +12 more
doaj   +1 more source