Results 91 to 100 of about 10,094,959 (327)

GENETICS IN ENDOCRINOLOGY: Genetic diagnosis of endocrine diseases by NGS: novel scenarios and unpredictable results and risks.

European Journal of Endocrinology, 2018
The technological advancements in genetics produced a profound impact on the research and diagnostics of non-communicable diseases. The availability of next-generation sequencing (NGS) allowed the identification of novel candidate genes but also an in ...
L. Persani, T. De Filippis, C. Colombo, D. Gentilini   +3 more
semanticscholar   +1 more source

Effects of Endocrine-Disrupting Heavy Metals on Human Health

Toxics, 2023
s Heavy metals play an important endocrine-disrupting role in the health consequences. However, the endocrine-disrupting mechanism of heavy metals is unclear. There are long-term and low-level metal/element exposure scenes for the human body in real life.
Dongling Liu, Qianhan Shi, Cuiqing Liu, Qinghua Sun, Xiang Zeng   +4 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Structural changes in intestinal enteroendocrine cells after ileal interposition in normal rats [PDF]

, 2011
INTRODUCTION: No therapeutic approach has significantly impacted the progression of diabetes. As early improvement of glicaemic control is observed after bariatric surgeries, there is currently a search for surgical procedures that can promote euglycemia
Aparecida Hirata, Bianca Marigliani, Gilmara Aguiar-Yamaguchi, Gustavo Miguel, José-Francisco Borborema, João-Luiz Azevedo, João-Luiz Azevedo, João-Luiz Azevedo, Karina Neves, Linda Bernardes, Lucas Leal, Marcelo Carlini, Maria Alves, Otavio Azevedo, Paolo Lourenco, Rudy Rocha, Wellington Cardia   +16 more
core   +2 more sources

Hair manifestations of endocrine diseases: A brief review

Indian Journal of Dermatology, Venereology and Leprology, 2018
Hair disorders are common in clinical practice and depending upon social and ethnic norms, it can cause significant psychosocial distress. Hair growth, cycling and density are regulated by many endogenous factors, mainly circulating hormones.
K. Vinay, G. Sawatkar, S. Dogra
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

综合心血管健康管理的泛危险因素

Journal of Diabetes, 2022
Cardiovascular diseases (CVDs) have become the leading cause of death in China. CVDs are mainly caused by multiple well‐known modifiable risk factors that are affected by socioeconomic and environmental determinants, lifestyle and behavioral choices, and
Ruizhi Zheng, Yu Xu, Mian Li, Jieli Lu, Min Xu, Tiange Wang, Zhiyun Zhao, Shuangyuan Wang, Hong Lin, Xiaoyun Zhang, Yufang Bi, Weiqing Wang, Guang Ning   +12 more
doaj   +1 more source

Reproductive Failure in UK Harbour Porpoises Phocoena phocoena : Legacy of Pollutant Exposure? [PDF]

, 2015
This research was supported by a Marie Curie International Outgoing Fellowship within the Seventh European Community Framework Programme (Project Cetacean-stressors, PIOF-GA-2010-276145 to PDJ and SM).
Barber, Jonathan L., Brownlow, Andrew, Davison, Nick, Deaville, Robert, Jepson, Paul D., Law, Robin J., Learmonth, Jennifer A., Murphy, Sinead, Penrose, Rod, Perkins, Matthew W., Pierce, Graham J., Read, Fiona L.   +11 more
core   +6 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Brain tissue- and cell type-specific eQTL Mendelian randomization reveals efficacy of FADS1 and FADS2 on cognitive function

Translational Psychiatry
Epidemiological studies suggested an association between omega-3 fatty acids and cognitive function. However, the causal role of the fatty acid desaturase (FADS) gene, which play a key role in regulating omega-3 fatty acids biosynthesis, on cognitive ...
Xueyan Wu, Lei Jiang, Hongyan Qi, Chunyan Hu, Xiaojing Jia, Hong Lin, Shuangyuan Wang, Lin Lin, Yifang Zhang, Ruizhi Zheng, Mian Li, Tiange Wang, Zhiyun Zhao, Min Xu, Yu Xu, Yuhong Chen, Jie Zheng, Yufang Bi, Jieli Lu   +18 more
doaj   +1 more source