Results 151 to 160 of about 10,094,959 (327)

The association of ideal cardiovascular health and its change with subclinical atherosclerosis according to glucose status: A prospective cohort study

Journal of Diabetes
Background An updated definition was developed to better evaluate cardiovascular health (CVH). We aimed to investigate whether optimal or improvement of six CVH metrics defined by new Life's Essential 8 (LE8) may counteract the risk of subclinical ...
Xiaojing Jia, Yilan Ding, Chunyan Hu, Hong Lin, Lin Lin, Xueyan Wu, Hongyan Qi, Shuangyuan Wang, Ruizhi Zheng, Jie Zheng, Min Xu, Yu Xu, Tiange Wang, Zhiyun Zhao, Yuhong Chen, Mian Li, Guang Ning, Weiqing Wang, Weiguo Hu, Yufang Bi, Jieli Lu   +20 more
doaj   +1 more source

The adverse role of endocrine disrupting chemicals in the reproductive system

Frontiers in Endocrinology
Reproductive system diseases pose prominent threats to human physical and mental well-being. Besides being influenced by genetic material regulation and changes in lifestyle, the occurrence of these diseases is closely connected to exposure to harmful ...
Jing Pan, Pengfei Liu, Xiao Yu, Zhongming Zhang, Jinxing Liu   +4 more
semanticscholar   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S., Allolio, B., Beuschlein, Felix, Chrousos, G. P., Jaursch-Hancke, C., Karl, M., Reincke, Martin, Travis, W.   +7 more
core  

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

New approaches for estimating risk from exposure to diethylstilbestrol. [PDF]

, 1999
A subgroup from a National Institute of Environmental Health Sciences, workshop concerned with characterizing the effects of endocrine disruptors on human health at environmental exposure levels considered the question, If diethylstilbestrol (DES) were ...
Cunha, GR, Forsberg, JG, Golden, R, Haney, A, Iguchi, T, Newbold, R, Swan, S, Welshons, W   +7 more
core   +2 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Transcriptome-wide Mendelian randomization during CD4+ T cell activation reveals immune-related drug targets for cardiometabolic diseases

Nature Communications
Immunity has shown potentials in informing drug development for cardiometabolic diseases, such as type 2 diabetes (T2D) and coronary artery disease (CAD). Here, we performed a transcriptome-wide Mendelian randomization (MR) study to estimate the putative
Xueyan Wu, Hui Ying, Qianqian Yang, Qian Yang, Haoyu Liu, Yilan Ding, Huiling Zhao, Zhihe Chen, Ruizhi Zheng, Hong Lin, Shuangyuan Wang, Mian Li, Tiange Wang, Zhiyun Zhao, Min Xu, Yuhong Chen, Yu Xu, Emma E. Vincent, Maria Carolina Borges, Tom R. Gaunt, Guang Ning, Weiqing Wang, Yufang Bi, Jie Zheng, Jieli Lu   +24 more
doaj   +1 more source

Applications of genomic research in pediatric endocrine diseases. [PDF]

Clin Exp Pediatr, 2023
Kim JH, Choi JH.
europepmc   +1 more source

CBmeter- a new medical device for early screening of metabolic diseases [PDF]

, 2018
Type 2 diabetes mellitus (T2DM) is a highly prevalent disease worldwide which is asymptomatic in about 44% of patients being critical to search for new ways of early diagnosis.
Brito, Gabriel, Fonseca-Pinto, Rui, Guarino, Maria Pedro, Lages, Marlene, Lopes, Nuno Vieira   +4 more
core  

Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction

Endocrine reviews
Multiple changes occur in hormonal regulation with aging and across various endocrine organs. These changes are associated with multiple age-related disorders and diseases.
M. Suda, Karl H Paul, Utkarsh Tripathi, Tohru Minamino, T. Tchkonia, James L. Kirkland   +5 more
semanticscholar   +1 more source