Results 81 to 90 of about 10,094,959 (327)

Genetic susceptibility, family history of diabetes and healthy lifestyle factors in relation to diabetes: A gene–environment interaction analysis in Chinese adults

Journal of Diabetes Investigation, 2021
Aims/Introduction To analyze the associations and interactions of the genetic susceptibility and family history of diabetes with lifestyle factors in relation to diabetes among Chinese adults.
Chaojie Ye, Jingya Niu, Zhiyun Zhao, Mian Li, Yu Xu, Jieli Lu, Yuhong Chen, Weiqing Wang, Guang Ning, Yufang Bi, Min Xu, Tiange Wang   +11 more
doaj   +1 more source

Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bowel Disease via Circulating Metabolites: A Mediation Mendelian Randomization Study

Metabolites, 2023
Epidemiological evidence regarding the effect of omega-3 polyunsaturated fatty acid (PUFA) supplementation on inflammatory bowel disease (IBD) is conflicting.
Xiaojing Jia, Chunyan Hu, Xueyan Wu, Hongyan Qi, Lin Lin, Min Xu, Yu Xu, Tiange Wang, Zhiyun Zhao, Yuhong Chen, Mian Li, Ruizhi Zheng, Hong Lin, Shuangyuan Wang, Weiqing Wang, Yufang Bi, Jie Zheng, Jieli Lu   +17 more
doaj   +1 more source

Cardiovascular features of possible autonomous cortisol secretion in patients with adrenal incidentalomas [PDF]

, 2018
Background: Low-grade incomplete post-dexamethasone cortisol suppression in patients with adrenal incidentalomas – recently defined as possible autonomous cortisol secretion (pACS) – has been associated with increased cardiovascular events and mortality.
Di Giorgio, Maria Rosaria, D’Aluisio, Denise, Giannetta, Elisa, Isidori, Andrea M., Lenzi, Andrea, Minnetti, Marianna, Morelli, Sergio, Pofi, Riccardo, Rizza, Laura, Sbardella, Emilia, Venneri, Mary Anna, Vestri, Annarita, Vinci, Fabio   +12 more
core   +2 more sources

Microbiota Implications in Endocrine-Related Diseases: From Development to Novel Therapeutic Approaches

Biomedicines
This comprehensive review article delves into the critical role of the human microbiota in the development and management of endocrine-related diseases. We explore the complex interactions between the microbiota and the endocrine system, emphasizing the ...
V. J. Clemente-Suárez, L. Redondo-Flórez, Alejandro Rubio-Zarapuz, Alexandra Martín-Rodríguez, J. F. Tornero-Aguilera   +4 more
semanticscholar   +1 more source

The impact of the gut microbiota on the reproductive and metabolic endocrine system

Gut microbes, 2021
As the gut microbiota exerts various effects on the intestinal milieu which influences distant organs and pathways, it is considered to be a full-fledged endocrine organ. The microbiota plays a major role in the reproductive endocrine system throughout a
Xinyu Qi, Chuyu Yun, Yanli Pang, J. Qiao
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Chain effect of lifecourse reproductive characteristics and body fat and muscle on cardiovascular disease in women: a Mendelian randomization study

Cardiovascular Diabetology
Background Delineating the causal chain effects of reproductive traits and fat- and muscle-related traits on cardiovascular disease (CVD) is essential for optimizing precision prevention and control of cardiovascular health in women.
Dong Liu, Chun Dou, Chaojie Ye, Lijie Kong, Zheng Zhu, Mingling Chen, Jie Zheng, Min Xu, Yu Xu, Mian Li, Zhiyun Zhao, Jieli Lu, Yuhong Chen, Guang Ning, Weiqing Wang, Yufang Bi, Tiange Wang   +16 more
doaj   +1 more source

Discordance between the triglyceride glucose index and HOMA-IR in incident albuminuria: a cohort study from China

Lipids in Health and Disease, 2021
Background To date, there have no study comparing the associations between TyG index and HOMA-IR on the risk of incident albuminuria. Accordingly, the objective of the present study is to use discordance analysis to evaluate the diverse associations ...
Wei Gao, Jialu Wang, Yan Chen, Hongmei Qiao, Xiaozhong Qian, Zhuojun Xin, Zhiyun Zhao, Tiange Wang, Yu Xu, Min Xu, Yufang Bi, Mian Li, Jinli Gao   +12 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The Effect of Canagliflozin on High-Density Lipoprotein Cholesterol and Angiopoietin-Like Protein 3 in Type 2 Diabetes Mellitus

Journal of Diabetes Research
Background. Diabetes mellitus is often accompanied by dyslipidemia. Sodium-glucose cotransporter-2 (SGLT2) inhibitors, as a novel therapeutic agent for the treatment of type 2 diabetes mellitus (T2DM), have been reported to exert effects on lipid, while ...
Simo Liu, Jing Ke, Xiaotong Feng, Zongwei Wang, Xin Wang, Longyan Yang, Dong Zhao   +6 more
doaj   +1 more source