Results 101 to 110 of about 311,005 (242)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Effective photoreduction of a nitroaromatic environmental endocrine disruptor by AgNPs functionalized on nanocrystalline TiO2

, 2015
"Unprecedented photoactivity of silver nanoparticles photodeposited on nanocrystalline TiO2 for the efficient reduction of 4-nitrophenol at room temperature is reported. The use of Na2SO3 as a harmless scavenger agent for the reduction of a nitroaromatic
Rodríguez González, Vicente, Hernández Gordillo, Agileo, Paraguay Delgado, Francisco, Sergio Obregón   +3 more
core   +1 more source

Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate

Current Research in Toxicology
Low molecular weight ortho-phthalates have been implicated in perturbing androgen pathways when administered during the masculinization programming window.
I.A. Lea, D. Feifarek, A. Mihalchik, M. Heintz, L. Haws, H. Nyambego, K. Goyak, C. Palermo, S.J. Borghoff   +8 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Perinatal exposure to the environmental pollutant butyl benzyl phthalate (BBP) induces sex-specific alterations in the neuro-immune-endocrine network in adult rats

Frontiers in Immunology
The plasticizer butyl benzyl phthalate (BBP), a ubiquitous endocrine disruptor, is commonly used in PVC products and can leach into the environment, leading to human exposure.
Diana Lizeth Ruiz-Antonio, Diana Lizeth Ruiz-Antonio, Karen E. Nava-Castro, Claudia Angelica Garay-Canales, Yair Rodrı́guez Santiago, María Del Sol Ríos-Avila, María Del Sol Ríos-Avila, César Antonio Zavala-Lopez, César Antonio Zavala-Lopez, Lenin Pavón, Gilberto Pérez-Sánchez, Lilia Diaz, Jorge Morales-Montor   +12 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

A critical review finds styrene lacks direct endocrine disruptor activity

, 2015
The European Commission lists styrene (S) as an endocrine disruptor based primarily on reports of increased prolactin (PRL) levels in S-exposed workers. The US Environmental Protection Agency included S in its list of chemicals to be tested for endocrine
Heinz-Peter Gelbke (809556), Edgar Leibold (809559), Susan Leanne Samson (809561), Mark Pemberton (809560), Marcy Banton (809558)   +4 more
core   +1 more source

Employment Trajectories of Patients With Systemic Lupus Erythematosus and Factors Driving Transitions Between States

Arthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) significantly impacts employment capacity. This study aimed to investigate the impact of burden of disease activity, damage, and treatment on employment outcomes and transitions in patients with SLE. Methods Using data from a single center, we analyzed employment transitions, adjusted mean disease activity ...
Javier Mencia‐Ledo, Zahi Touma, Laura Whittall Garcia, Dafna D. Gladman, Behdin Nowrouzi‐Kia   +4 more
wiley   +1 more source

Studies on Removal of Emerging Endocrine Disruptor Compounds from Aqueous Phase by Synthesized Nanozeolites

, 2018
Endocrine disruptor compounds (EDCs) are exogenous chemicals that interfere with the endocrine (hormone regulating) system by mimicking or blocking natural hormones of exposed organisms, even at trace amounts (1-10 mg/L).
Goyal, Nitin
core   +1 more source