Results 111 to 120 of about 22,130 (290)

Biomonitoring Pilot Surveys of Zearalenone in Breastmilk and the Urine of Children in Central Portugal

Toxins
Zearalenone (ZEA) is a mycotoxin that acts primarily as an endocrine disruptor. Biomonitoring studies are needed to assess exposure and risk, particularly among vulnerable groups.
Sofia Duarte, Inês Duarte, Myrella Duarte, Ana Paiva, Ricardo Cabeças, Liliana J. G. Silva, André M. P. T. Pereira, Celeste Lino, Angelina Pena   +8 more
doaj   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Assessment of the endocrine disrupting properties of Bisphenol AF according to the EU criteria and ECHA/EFSA guidance

EFSA Journal, 2019
Endocrine disruptors (EDs) are exogenous compounds that interfere with the hormone system, affecting human health and environment. Specific legislative obligations have been introduced in the European Union (EU) to gradually eliminate EDs in water ...
Karolinska Institutet, Institute of Environmental Medicine, Sweden, Laura Escrivá, Annika Hanberg, Johanna Zilliacus, Anna Beronius   +4 more
doaj   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

Quantification of Bisphenol A in the Saliva of Patients Wearing Clear Aligners

Dentistry Journal
Background/Objectives: To analyze the behavior and release of bisphenol A (BPA) in the saliva of patients wearing clear aligners, and to evaluate differences in BPA levels between patients treated with aligners from the market-leading brand and those ...
Andrea Vitores-Calero, Verónica García-Sanz, Vanessa Paredes-Gallardo, Natalia Zamora-Martínez, Beatriz Tarazona-Álvarez   +4 more
doaj   +1 more source

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

Advanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez, Jose I. Garcia‐Peiro, Jose L. Hueso, Eduardo Caleiras, Laura Notario, Felipe Hornos, Pilar Martin‐Duque, Antonio De la Vieja, Jesus Santamaria   +8 more
wiley   +1 more source

Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate

Current Research in Toxicology
Low molecular weight ortho-phthalates have been implicated in perturbing androgen pathways when administered during the masculinization programming window.
I.A. Lea, D. Feifarek, A. Mihalchik, M. Heintz, L. Haws, H. Nyambego, K. Goyak, C. Palermo, S.J. Borghoff   +8 more
doaj   +1 more source

Disrupting effect of methanolic extract from Prosopis torquata (CAV. EX LAG.) fruits on male Wistar rats [PDF]

, 2015
Los disruptores endocrinos de plantas causan anomalías en el sistema reproductivo de los mamíferos. Estudiamos los efectos del extracto metanólico (MEx) del fruto de Prosopis torquata en la reproducción, histología y morfología del sistema reproductivo ...
Aguilera Merlo, Claudia, Carrasco, Mirta, Díaz, Yésica, Mangione, Antonio Marcelo, Salinas, Adriana P.   +4 more
core  

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source