Results 61 to 70 of about 34,824 (338)

Hypoxia does not influence the response of fish to a mixture of estrogenic chemicals [PDF]

, 2009
The official published version can be obtained from the link below - Copyright @ 2009 American Chemical SocietyChemical risk assessment procedures assign a major role to standardized toxicity tests, in which the response of a particular organism to a ...
Beresford, NA, Brian, JV, Fantinati, A, Marcomini, A, Pojana, G, Sumpter, JP, Walker, J   +6 more
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Endocrine-Disrupting Chemicals: Testing to Protect Future Generations [PDF]

, 2011
Endocrine-disrupting chemicals (EDCs) are a class of chemicals that interferes with human hormone processes. EDCs are omnipresent: pesticides, plastics, and drugs, among other common chemicals, all demonstrate endocrine-disrupting properties.
Van der Mude, Alana
core  

The endocrine disruptor TCDD modulates microRNA expression in preimplantation mouse embryos and spheroids attachment on human endometrial epithelial cells in vitro [PDF]

, 2010
Conference Theme: The Intersection Between Genetics, Genomics, and Reproductive BiologyThe endocrine disruptor (ED) is an exogenous substance that acts on the endocrine system and modulates normal physiological functions of the body. Although EDs such as
Cheung, TY, Kodithuwakku, SP, Lee, KF, Liu, WM, Tsang, H, Wong, CKC, Yeung, WSB   +6 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Is Japan at low risk for PFAS immunotoxicity?: human biomonitoring study in contaminated areas in Japan

Environmental Health and Preventive Medicine
Background: Per- and polyfluoroalkyl substances (PFAS) are now considered global contaminants posing health risks. Recent human biomonitoring data in Japan are presented.
Zhaoqing Lyu, Kouji H. Harada, Junko Kimura-Kuroda, Yasuharu Tokuda   +3 more
doaj   +1 more source

Degradation of 2-Chlokophenol in Water Using Advanced Oxidation Processes [PDF]

, 2005
The presence of endocrine disruptor chemicals (EDCs) in treated wastewater lately, is alarming. Chlorophenols, an endocrine disruptor chemical compound is hardly eliminated in water using conventional treatment.
Leong, Jin Hoong
core  

Combined transcriptomic-(1)H NMR metabonomic study reveals yhat monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes [PDF]

, 2011
Adipose tissue is a major storage site for lipophilic environmental contaminants. The environmental metabolic disruptor hypothesis postulates that some pollutants can promote obesity or metabolic disorders by activating nuclear receptors involved in the ...
Beale E. G., Beale E. G., Becker K., Beckonert O., Berman T., Cadoudal T., Cadoudal T., Chakravarty K., Chantal Benelli, Christianson J. L., Chui P. C., Claude Forest, Claus S. P., Cloarec O., Desvergne B., Durmaz E., Ellero S. L., Eriksson L., Eubank D. W., Feige J. N., Feige J. N., Franck Letourneur, Franckhauser S., Fukuwatari T., Gregoire F. M., Grun F., Grun F., Guan H. P., Hanson R. W., Hanson R. W., Hatch E. E., Huang da W., Huber W. W., Hurst C. H., Isabelle de Waziers, Martinelli M. I., Millward C. A., Mullerova D., Nicolas Cagnard, Okuno A., Philippe H. Beaune, Rink J. D., Roberts L. D., Roberts R. A., Sandrine Ellero-Simatos, Sandrine P. Claus, Sears D. D., Si Y., Stahlhut R. W., Su X., Targett-Adams P., Tordjman J., Trygg J., Tusher V. G., van Harmelen V., Veselkov K. A., Weuve J., Yoo H., Zancanaro C., Zhang Y. H.   +59 more
core   +2 more sources

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Pyriproxyfen, villain or good guy? A brief review [PDF]

Archives of Endocrinology and Metabolism
Pyriproxyfen (PPF) acts as a juvenile growth regulator, interfering with normal metamorphosis and blocking the development of insects into adulthood. Although the World Health Organization (WHO) considers the use of PPF at a concentration of 0.01 mg/L as
Andressa Pereira Cabral, Fabrício Pereira dos Santos Maia, D’Angelo Carlo Magliano, Jones Bernardes Graceli, Paula Soares, Eduardo Andrés Rios Morris, Leandro Miranda-Alves   +6 more
doaj   +1 more source