Results 41 to 50 of about 22,130 (290)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich +5 more
wiley +1 more source
Climate change and disaster impact reduction [PDF]
, 2008 Based on papers presented at the 'UK - South Asia Young Scientists and Practitioners Seminar on Climate Change and Disaster Impact Reduction' held at Kathmandu, Nepal on 5-6 June ...
Aryal, Komal, Gadema, Zaina
core
The Science of Endocrine Disruption - Will It Change the Scope of Products Liability Claims? [PDF]
, 2000 The FDA Food Quality Protection Act of 1996 and amendments to the EPA Safe Drinking Water Act require the EPA Administrator, in consultation with the Secretary of Health and Human Services, to develop a screening program for endocrine disrupting effects.
Fassuliotis, Karen
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Opening the Industry Playbook: Myths and Truths in the Debate over BPA Regulation [PDF]
, 2011 For the last two decades, scientists have amassed evidence that bisphenol A (BPA) poses a threat to human health. Although scientists have targeted BPA as a public health concern, plastics industry lobbyists have attempted to thwart the efforts of ...
McGarity, Thomas +3 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Endocrine disrupters, microRNAs, and primordial germ cells: a dangerous cocktail [PDF]
, 2016 29 p.-2 fig.Endocrine-disrupting chemicals (EDCs) are environmental pollutants that may change the homeostasis of the endocrine system, altering the differentiation of germ cells with consequences for reproduction.
Brieño-Enríquez, Miguel A. +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Environmental contaminants exposure and preterm birth: a systematic review [PDF]
, 2019 Preterm birth is an obstetric condition associated with a high risk of infant mortality and morbidities in both the neonatal period and later in life, which has also a significant public health impact because it carries an important societal economic ...
Benedetti Panici, Pierluigi +5 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source