Results 61 to 70 of about 4,312 (242)

Endocrine disruptors also function as nervous disruptors and can be renamed endocrine and nervous disruptors (ENDs)

Toxicology Reports, 2021
Endocrine disruption (ED) and endocrine disruptors (EDs) emerged as scientific concepts in 1995, after numerous chemical pollutants were found to be responsible for reproductive dysfunction. The World Health Organization established in the United Nations Environment Programme a list of materials, plasticizers, pesticides, and various pollutants ...
Gilles-Eric Seralini, Gerald Jungers
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The endocrine disruptor 17β-trenbolone alters the relationship between pre- and post-copulatory sexual traits in male mosquitofish (Gambusia holbrooki)

, 2021
The endocrine disruptor 17β-trenbolone alters the relationship between pre- and post-copulatory sexual traits in male mosquitofish (Gambusia ...
JM Martin (15814520), SL Hannington (19329763), TE Ecker (15838025), M Saaristo (19329766), BBM Wong (14452728), MK O'Bryan (19329769), H Tan (9768602), MG Bertram (14466561)   +7 more
core  

AMAZON ACAI AND PINEAPPLE RESIDUES INDUCE THE ENZYME LACCASE IN Pleurotus ostreatus: APPLICATION TO BISPHENOL A BIOREMEDIATION [PDF]

Química Nova
Bisphenol A (BPA), an endocrine disruptor used in different commercial polymers, is a persistent pollutant commonly found in effluents. Conventional wastewater treatment processes have low chemical removal efficiency and are expensive.
Jhessica Cavalcante de Souza Golveia, Elaine Sousa Nunes, Thiago Souza Bulhões, Jerônimo Raimundo de Oliveira Neto, Luiz Carlos da Cunha, Luiza Cintra Campos, Mariângela Fontes Santiago, Fernando Schimidt   +7 more
doaj   +1 more source

Demographic Assessment of Mono(2‐ethylhexyl) Phthalate (MEHP) and Monoethyl Phthalate (MEP) Concentrations in Common Bottlenose Dolphins (Tursiops truncatus) From Sarasota Bay, FL, USA

GeoHealth, 2021
Common bottlenose dolphins (Tursiops truncatus) have previously demonstrated exposure to phthalate esters. Phthalates and phthalate esters are commonly added to consumer goods to enhance desirable properties.
M. K. Dziobak, R. S. Wells, E. C. Pisarski, E. F. Wirth, L. B. Hart   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Rational Selection of the 3D Structure of Biomacromolecules for Molecular Docking Studies on the Mechanism of Endocrine Disruptor Action [PDF]

, 2016
Molecular modeling has become an essential tool in predicting and simulating endocrine disrupting effects of chemicals. A key prerequisite for successful application of molecular modeling lies in the correctness of 3D structure for biomacromolecules to ...
Shi, LL, jwchen@dlut.edu.cn, Liu, HH, Liu, JB (reprint author), Minist Environm Protect, Nanjing Inst Environm Sci, 8 Jiangwangmiao Steet, Nanjing 210042, Jiangsu, Peoples R China., Li, F, Chen, JW (reprint author), Dalian Univ Technol, Sch Environm Sci & Technol, Linggong Rd 2, Dalian 116024, Peoples R China. Email:ljn@nies.org, Li, XH, Chen, JW, Yang, XH, Liu, JB   +9 more
core   +2 more sources

Is Japan at low risk for PFAS immunotoxicity?: human biomonitoring study in contaminated areas in Japan

Environmental Health and Preventive Medicine
Background: Per- and polyfluoroalkyl substances (PFAS) are now considered global contaminants posing health risks. Recent human biomonitoring data in Japan are presented.
Zhaoqing Lyu, Kouji H. Harada, Junko Kimura-Kuroda, Yasuharu Tokuda   +3 more
doaj   +1 more source

Pyriproxyfen, villain or good guy? A brief review [PDF]

Archives of Endocrinology and Metabolism
Pyriproxyfen (PPF) acts as a juvenile growth regulator, interfering with normal metamorphosis and blocking the development of insects into adulthood. Although the World Health Organization (WHO) considers the use of PPF at a concentration of 0.01 mg/L as
Andressa Pereira Cabral, Fabrício Pereira dos Santos Maia, D’Angelo Carlo Magliano, Jones Bernardes Graceli, Paula Soares, Eduardo Andrés Rios Morris, Leandro Miranda-Alves   +6 more
doaj   +1 more source