Results 101 to 110 of about 1,333,671 (322)

Recurrent laryngeal nerve monitoring by flexible laryngoscopy during thyroid radiofrequency ablation in the awake patient

Frontiers in Endocrinology
ObjectiveAlthough radiofrequency ablation (RFA) is a safe and effective non-surgical treatment for benign thyroid nodules, injury to the recurrent laryngeal nerve (RLN), is a potential and feared complication. Intermittent voice checks have been proposed
Marsida Teliti, Marsida Teliti, Antonio Occhini, Rodolfo Fonte, Laura Croce, Laura Croce, Benedetto Calì, Federica Antonella Ripepi, Andrea Carbone, Mario Rotondi, Mario Rotondi, Spyridon Chytiris   +11 more
doaj   +1 more source

Endocrine Disruption by Mixtures in Topical Consumer Products

Cosmetics, 2018
Endocrine disruption has been gathering increasing attention in the past 25 years as a possible new threat for health and safety. Exposure to endocrine disruptor has been progressively linked with a growing number of increasing disease in the human ...
Emiliano Ripamonti, Elena Allifranchini, Stefano Todeschi, Elena Bocchietto   +3 more
doaj   +1 more source

Disruptores endocrinos y su camino hacia el desequilibrio metabólico

Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2020
El presente artículo de revisión tiene como objetivo presentar, de forma resumida, la evidencia que existe sobre las repercusiones metabólicas a nivel de obesidad y diabetes, que se genera como consecuencia de la exposición a sustancias químicas ...
P. Sánchez, M. Zanabria, S. Latorre, J. Calvache, A. Coy, W. Rojas   +5 more
doaj   +1 more source

Guidance for the identification of endocrine disruptors in the context of Regulations (EU) No 528/2012 and (EC) No 1107/2009

EFSA journal. European Food Safety Authority, 2018
This Guidance describes how to perform hazard identification for endocrine‐disrupting properties by following the scientific criteria which are outlined in Commission Delegated Regulation (EU) 2017/2100 and Commission Regulation (EU) 2018/605 for ...
N. Andersson, Maria Arena, D. Auteri, S. Barmaz, E. Grignard, A. Kienzler, P. Lepper, A. Lostia, S. Munn, Juan Manuel Parra Morte, F. Pellizzato, J. Tarazona, A. Terron, S. C. van der Linden   +13 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Is there a causal association between genotoxicity and the imposex effect? [PDF]

, 2006
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Josephine A. Hagger, Michael H. Depledge, Jörg Oehlmann, Susan Jobling, Tamara S. Galloway, Colborn T, Collins MKL, Cooke H, Depledge MH, Gibbs PE, Harring KE, Harris JO, Laruelle F, Smith BS   +13 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The epigenetic impacts of endocrine disruptors on female reproduction across generations†

Biology of Reproduction, 2019
Humans and animals are repeatedly exposed to endocrine disruptors, many of which are ubiquitous in the environment. Endocrine disruptors interfere with hormone action; thus, causing non-monotonic dose responses that are atypical of standard toxicant ...
Saniya Rattan, J. Flaws
semanticscholar   +1 more source

Thresholds and Endocrine Disruptors: An Endocrine Society Policy Perspective

Journal of the Endocrine Society, 2020
The concept of a threshold of adversity in toxicology is neither provable nor disprovable. As such, it is not a scientific question but a theoretical one.
B. Demeneix, Laura N. Vandenberg, R. Ivell, R. Zoeller   +3 more
semanticscholar   +1 more source