Results 11 to 20 of about 171,806 (336)

To what extent does photoperiod affect cattle reproduction? Clinical perspectives of melatonin administration [PDF]

open access: yes, 2020
The seasonality of reproduction in most mammals is dictated by photoperiod, temperature and nutrition. Melatonin, mainly synthesized in the pineal gland, is generally accepted as the active mediator of photoperiod responses including reproduction.
De Rensis, F.   +3 more
core   +1 more source

Investigating the Association Between rs2439302 Polymorphism and Thyroid Cancer: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Surgery, 2022
Background and AimsThe extent of surgical treatment for most patients with thyroid cancer (TC) remains controversial and varies widely. As an emerging technology, genetic testing facilitates tumor typing and disease progression monitoring and is expected
Yawen Guo   +11 more
doaj   +1 more source

A Systematic Pan-Cancer Analysis of CASP3 as a Potential Target for Immunotherapy

open access: yesFrontiers in Molecular Biosciences, 2022
CASP3 is the gene encoding caspase-3, a specific protease that cleaves substrates such as poly-ADP ribose polymerase and acetyl-DEVD-7-amino-4-methylcoumarin. This enzymatic activity leads to DNA fragmentation, which is a hallmark of apoptosis.
Zheng Zhou   +9 more
doaj   +1 more source

Genetic regulation of pituitary gland development in human and mouse [PDF]

open access: yes, 2009
Normal hypothalamopituitary development is closely related to that of the forebrain and is dependent upon a complex genetic cascade of transcription factors and signaling molecules that may be either intrinsic or extrinsic to the developing Rathke’s ...
Aarskog   +321 more
core   +2 more sources

Recent descriptions on physiological concepts of the pineal gland: what's new?

open access: yesRomanian Neurosurgery, 2021
The pineal gland is an endocrine organ located in the cranial vault. Its endocrine function has been extensively studied and has been found to be the cause of important regulatory functions in the physiology of the human body.
Dany Leonardo Contreras-De La Hoz   +11 more
doaj   +2 more sources

Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]

open access: yes, 2016
We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M.   +7 more
core   +2 more sources

Sexual Differentiation of Circadian Clock Function in the Adrenal Gland [PDF]

open access: yes, 2016
Sex differences in glucocorticoid production are associated with increased responsiveness of the adrenal gland in females. However, the adrenal-intrinsic mechanisms that establish sexual dimorphic function remain ill defined. Glucocorticoid production is
Evans, Jennifer A.   +5 more
core   +2 more sources

Multiple endocrine neoplasia type 4: a new member of the MEN family

open access: yesEndocrine Connections, 2023
Objective: Multiple endocrine neoplasia type 4 (MEN4) is caused by a CDKN1B germline mutation first described in 2006. Its estimated prevalence is le ss than one per million. The aim of this study was to define the disease characteristics.
Hélène Singeisen   +9 more
doaj   +1 more source

Ligula intestinalis (Cestoda: Pseudophyllidea): an ideal fish-metazoan parasite model? [PDF]

open access: yes, 2010
Since its use as a model to study metazoan parasite culture and in vitro development, the plerocercoid of the tapeworm, Ligula intestinalis, has served as a useful scientific tool to study a range of biological factors, particularly within its fish ...
Carter, V, Dufour, S, Hoole, D
core   +1 more source

Reversible Severe Rhabdomyolysis Associated with Thyrotoxic Hypokalemic Periodic Paralysis

open access: yesCase Reports in Neurology, 2021
We report a case of reversible symptomatic rhabdomyolysis associated with thyrotoxic hypokalemic periodic paralysis. The patient had neither past medical nor family history of either disorder.
Praewchompoo Sathirapanya   +2 more
doaj   +1 more source

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