Results 61 to 70 of about 931,208 (372)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Endocrine mucin-producing sweat gland carcinoma of the eyelid – A diagnostic challenge

Indian Journal of Pathology and Microbiology
Skin adnexal or sweat gland neoplasms are rare adnexal tumors that pose a diagnostic challenge for both ophthalmologists and pathologists. Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is an uncommon low grade carcinoma of eccrine ducts with a
Viral M. Bhanvadia, Ravija Kathiara, Ami Shah, Wilhemina Asari   +3 more
doaj   +1 more source

Study of Serum Leptin in Well-differentiated Thyroid Carcinoma: Correlation with Patient and Tumor Characteristics [PDF]

, 2014
Background There is a proven relationship between obesity and several cancers including breast, endometrium, colorectal, and esophagus. With the increasing incidence of both obesity and thyroid cancer, we designed the present study to investigate a ...
Abdel-Aziz, TE, Elwafa, RA, Elwafa, WA, Rehem, RA   +3 more
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The Endocrine Glands [PDF]

The American Biology Teacher, 1940
A gland is an organ which takes something from the blood or other circulating mediunm and manufactures therefrom a secretioni which it delivers to the body as needed. Roughly there are two kinds of glands: those which deliver their secretion through ducts or tubes and those whose secretion is picked up directly bv the blood or lymph as it eirculates ...
  +5 more sources

Autoimmune Polyglandular Syndrome Type-2 A Case Report on a Rare Disease

Pakistan Armed Forces Medical Journal, 2023
Autoimmune polyglandular syndromes (APS) are rare disorders involving multiple endocrine and non-endocrine organs. These are often difficult to diagnose, as the clinical presentation of these is insidious.
Wahaj Ul Hassan, Ummarah Zafar Farid, Kamran Ali, Umer Naseer   +3 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Endocrine Disorders in Nephrotic Syndrome—A Comprehensive Review

Biomedicines
Nephrotic syndrome is a clinical syndrome characterized by massive proteinuria, called nephrotic range proteinuria (over 3.5 g per day in adults or 40 mg/m2 per hour in children), hypoalbuminemia, oncotic edema, and hyperlipidemia, with an increasing ...
Maja Mizdrak, Bozo Smajic, Ivan Mizdrak, Tina Ticinovic Kurir, Marko Kumric, Ivan Paladin, Darko Batistic, Josko Bozic   +7 more
doaj   +1 more source

Total or near-total thyroidectomy versus subtotal thyroidectomy for multinodular non-toxic goitre in adults [PDF]

, 2015
Background Total thyroidectomy (TT) and subtotal thyroidectomy (ST) are worldwide treatment options for multinodular non-toxic goitre in adults.
Arezzo, Alberto, Avenia, Nicola, Barczyñski, Marcin, Cirocchi, Roberto, D'Andrea, Vito, DI ROCCO, Giorgio, Guarino, Salvatore, Randolph, Justus, Santoro, Alberto, Trastulli, Stefano   +9 more
core   +2 more sources