Applied Sciences, 2020 The pineal gland is an endocrine gland whose main function is the biosynthesis and secretion of melatonin, a hormone responsible for regulating circadian rhythms, e.g., the sleep/wake cycle.
Dariusz Chlubek, Maciej Sikora
doaj +1 more source
Consequences of Postnatally Elevated Insulin-Like Growth Factor-II in Transgenic Mice: Endocrine Changes and Effects on Body and Organ Growth. [PDF]
, 1994 Insulin-like growth factor-II (IGF-II) is an important regulator of embryonic growth and differentiation, but its function in postnatal life is unclear. To address this point, we generated transgenic mice harboring fusion genes in which a human IGF-II
Blum, Werner F. +4 more
core +1 more source
Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid
Advanced Functional Materials, EarlyView.In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang +16 more
wiley +1 more source
Reaction of chickens to graduated length of exposure to stress [PDF]
The reactions of 60 day old chickens Arbor Acres 60 X Vantress to immobilization stress lasting 1/2, 1, 2, 4 hours and to application of ACTH, manifested by activity changes in the systems hypophysis-adrenal gland and hypophysis-thyroid gland were ...
Faberova, A., Grom, A., Nvota, J.
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Acromegaly: pathogenesis & treatment [PDF]
, 2019 Acromegaly is a multi-system disorder whose etiology is most often traced back to a growth hormone-secreting pituitary adenoma (PA). Growth hormone (GH) secretion promotes insulin-like growth factor 1 (IGF-1) release from peripheral tissues, leading to ...
Tilvawala, Megha
core
Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]
, 2013 Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher +3 more
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Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Immunnohistochemical determination of calbindin distribution in gastrointestinal tract organs and pancreas, and in hypophysis, adrenal medulla and kidneys of guinea pigs [PDF]
Eurasian Journal of Veterinary SciencesThe distribution ol calbindin in thyroid, parathyroid, piluilary and adrenals, and in gastrointestinal tract epilhelium, pancreas and in Ihe kidney has been investigated immunohistochemically using an antiserum raised against the 28k Da calbindin from ...
Berrin Gençer Tarakçı, Sema Timurkaan
doaj
Study of Serum Leptin in Well-differentiated Thyroid Carcinoma: Correlation with Patient and Tumor Characteristics [PDF]
, 2014 Background There is a proven relationship between obesity and several cancers including breast, endometrium, colorectal, and esophagus. With the increasing incidence of both obesity and thyroid cancer, we designed the present study to investigate a ...
Abdel-Aziz, TE +3 more
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3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source