Results 131 to 140 of about 179,235 (348)

Effect of alcohol on the endocrine glands of pregnant wistar rats

Sahel Medical Journal, 2010
Background: An investigation was conducted to determine the effect of alcohol on some endocrine glands of pregnant Wistar rats. Methods: Thirty female Wistar rats divided into 2 groups of 15 each were used.
J E Onu, B O Oke, P C Ozebge, J O Omirinde   +3 more
doaj  

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Features of reproduction and assisted reproduction in the white (Ceratotherium simum) and black (Diceros bicornis) rhinoceros [PDF]

, 2015
Despite the worldwide increase of rhinoceros calf numbers, the growth of the population of white and black rhinoceros is slowing down mainly due to anthropogenic causes, such as poaching and habitat loss.
Govaere, Jan, Van Soom, Ann, van Zijl Langhout, M, Ververs, Cyrillus   +3 more
core  

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Parathyroid hormone-related peptide stimulates intestinal strontium absorption in Camels (Camelus dromedarius) [PDF]

, 2008
The present work was undertaken to evaluate the stimulatory effect of Parathyroid hormone-related peptide (PTHrP) on the intestinal calcium (Ca) absorption using stable strontium (Sr) as a surgoate marker in 10 Camels.
Coxam, Véronique, Davicco, Marie Jeanne, El Abbadi, Najia, El Khasmi, Mohammed, Farh, Mohamed, Faye, Bernard, Riad, Fouad, Safwate, Abdallah   +7 more
core  

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Objective assessment of functional and motor-cognitive outcomes among asymptomatic primary hyperparathyroidism patients undergoing parathyroidectomy using wearable technologies: a pilot study towards better informed clinical decision-making [PDF]

, 2017
For the past 40 years, most patients with Primary Hyperparathyroidism (PHPT) have presented with the asymptomatic form of PHPT. Despite the dominance of the asymptomatic PHPT phenotype, current National Institutes of Health (NIH) indications for ...
Siddiqi, Noreen
core  

Endocrinology: Patients suffering from H63D syndrome are at high risk to develop clinically relevant endocrine abnormalities affecting their adrenal glands as well as their HPA and SMA axes

, 2022
Marius Lazar, David Seideman, Lucas Smith, Sofia Makri, Benjamin Steinberg, Adrian Tudor, Tamara Dimitrikova, Olga Ivanova, Marianne Wagner, Alexander Louw, Margaret Pistorius, Riku Honda, Boris Cohen, Alexander Strelkov, Susan Tudor, Georg Schuster, Carolina Diamandis   +16 more
openalex   +2 more sources

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

The study on the risk of other endocrine glands autoimmune diseases in patients with type 1 diabetes mellitus. [PDF]

Medicine (Baltimore), 2020
Liu Y, Chen S, Zhang D, Li Z, Wang X, Xie X, Zhu H, Ren L, Wang L.   +8 more
europepmc   +1 more source