Results 1 to 10 of about 1,070,407 (313)

Beta-Hydroxybutyric Acid Inhibits Renal Tubular Reabsorption via the AKT/DAB2/Megalin Signalling Pathway

open access: yesJournal of Diabetes Research, 2022
Aim. Patients with diabetic ketosis often exhibit albuminuria. We previously found that acute hyperglycaemia can cause nephrotoxic injury. Here, we explored whether an excessive ketone body level causes kidney injury and the potential underlying ...
Minxia Zuo   +10 more
doaj   +1 more source

Implication of extrinsic and intrinsic apoptotic pathways in the targeted therapy of hepatocellular carcinoma using aptamer-labeled viramidine nanoparticles

open access: yesBMC Cancer, 2022
Hepatocellular carcinoma (HCC) is a global health problem with regional differences in epidemiological statistics. Co-assembling the drug nanoparticles and targeting moieties could improve the therapeutic delivery of anti-cancer drugs.
Ahmed A. Abd-Rabou   +2 more
doaj   +1 more source

Identification of SRS transcription factor family in Solanum lycopersicum, and functional characterization of their responses to hormones and abiotic stresses

open access: yesBMC Plant Biology, 2023
The SHI RELATED SEQUENCE (SRS) family plays a vital role in the development of multiple plant organs such as floral meristem determinacy, organ morphogenesis, and signal transduction.
Wang Lu   +10 more
doaj   +1 more source

Genome-wide identification, characterization and expression analysis of BES1 gene family in tomato

open access: yesBMC Plant Biology, 2021
Background As the key regulators in BR signaling, BES1 family genes regulate thousands of target genes involved in various development processes. So far, the functions of BES1 family are poorly understood in tomato, and a comprehensive genomic and ...
Deding Su   +6 more
doaj   +1 more source

The targeted delivery of chitosan nanoparticles to treat indoxacarb: induced lung fibrosis in rats

open access: yesBulletin of the National Research Centre, 2022
Background This study evaluated the effects of chitosan nanoparticles (Ch-NPs) on indoxacarb (INDOX)-induced pulmonary fibrosis in in vivo and in vitro models. In in vivo studies, 40 male albino rats were randomly divided into four groups (10 rats/group):
Naglaa A. Ali   +3 more
doaj   +1 more source

Roles of Auxin in the Growth, Development, and Stress Tolerance of Horticultural Plants

open access: yesCells, 2022
Auxin, a plant hormone, regulates virtually every aspect of plant growth and development. Many current studies on auxin focus on the model plant Arabidopsis thaliana, or on field crops, such as rice and wheat.
Qiongdan Zhang   +4 more
doaj   +1 more source

secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila [PDF]

open access: yes, 2019
Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products.
Dent, J.   +6 more
core   +2 more sources

Tomato transcriptome and mutant analyses suggest a role for plant stress hormones in the interaction between fruit and Botrytis cinerea. [PDF]

open access: yes, 2013
Fruit-pathogen interactions are a valuable biological system to study the role of plant development in the transition from resistance to susceptibility. In general, unripe fruit are resistant to pathogen infection but become increasingly more susceptible
Ann L T Powell   +4 more
core   +2 more sources

Influence of Light-Emitting Diode-Derived Blue Light Overexposure on Rat Ocular Surface

open access: yesJournal of Ophthalmology, 2023
We aim to investigate the effect of overexposure to blue light on the rat ocular surface and explore the potential mechanisms. 450 nm light-emitting diode (LED) derived light at 1000 lux was used to irradiate SD rats, 12 hours a day, for consecutive 28 ...
Li Nan   +5 more
doaj   +1 more source

Sex hormones in allergic conjunctivitis: altered levels of circulating androgens and estrogens in children and adolescents with vernal keratoconjunctivitis [PDF]

open access: yes, 2015
PURPOSE: Vernal keratoconjunctivitis (VKC) is a chronic allergic disease mainly affecting boys in prepubertal age and usually recovering after puberty.
Bonini, S.   +4 more
core   +4 more sources

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