Results 11 to 20 of about 512,673 (268)

Hormones, damned hormones, and statistics [PDF]

BJOG: An International Journal of Obstetrics & Gynaecology, 2017
Deputy Editor‐in‐Chief, Dr Michael Marsh, discusses his top articles from this issue in an audio podcast available at: https://soundcloud.com/bjog/september-editors-choice-2017.
openaire   +2 more sources

TREATMENT OF GROWTH-HORMONE DEFICIENCY WITH GROWTH-HORMONE-RELEASING HORMONE

The Lancet, 1987
18 prepubertal growth-hormone (GH)-deficient children were treated with twice-daily subcutaneous injections of a growth-hormone-releasing hormone analogue, GHRH (1-29) NH2. In 12 of the children the height velocity rose on GHRH treatment, and 8 were judged to have shown a worthwhile response to therapy in that their height velocities during the first 6
Ross, R.J.M., Tsagarakis, S., Grossman, A., Preece, M.A., Rodda, C., Davies, P.S.W., Rees, L.H., Savage, M.O., Besser, G.M.   +8 more
openaire   +5 more sources

AGER1 deficiency-triggered ferroptosis drives fibrosis progression in nonalcoholic steatohepatitis with type 2 diabetes mellitus

Cell Death Discovery, 2023
Hyperglycemia is an independent risk factor for the rapid progression of nonalcoholic steatohepatitis (NASH) to liver fibrosis with an incompletely defined mechanism.
Yihui Gong, Zijun Liu, Yuanyuan Zhang, Jun Zhang, Yin Zheng, Zhongming Wu   +5 more
doaj   +1 more source

Gallic acid against hepatocellular carcinoma: An integrated scheme of the potential mechanisms of action from study

Tumor Biology, 2017
The global burden of hepatocellular carcinoma is increasing; actually, it is estimated as 750,000 new cases annually. This study was initiated to emphasize the possibility that gallic acid could alleviate hepatocarcinogenesis in vivo .
Hadeer A Aglan, Hanaa H Ahmed, Sayed A El-Toumy, Nadia S Mahmoud   +3 more
doaj   +1 more source

Ras Guanine Nucleotide-Releasing Protein-4 Inhibits Erythropoietin Production in Diabetic Mice with Kidney Disease by Degrading HIF2A [PDF]

Diabetes & Metabolism Journal
Background In acute and chronic renal inflammatory diseases, the activation of inflammatory cells is involved in the defect of erythropoietin (EPO) production.
Junmei Wang, Shuai Huang, Li Zhang, Yixian He, Xian Shao, A-Shan-Jiang A-Ni-Wan, Yan Kong, Xuying Meng, Pei Yu, Saijun Zhou   +9 more
doaj   +1 more source

PACS-2 attenuates diabetic kidney disease via the enhancement of mitochondria-associated endoplasmic reticulum membrane formation

Cell Death and Disease, 2021
The altered homeostasis of mitochondria-associated endoplasmic reticulum (ER) membranes (MAM) was closely associated with the pathological process of nervous system diseases and insulin resistance.
Mei Xue, Ting Fang, Hongxi Sun, Ying Cheng, Ting Li, Chaofei Xu, Chao Tang, Xiaohuan Liu, Bei Sun, Liming Chen   +9 more
doaj   +1 more source

SlMYB75, an MYB-type transcription factor, promotes anthocyanin accumulation and enhances volatile aroma production in tomato fruits

Horticulture Research, 2019
Genetics: one small tweak, one giant leap for tomatoes A single gene has been identified in tomatoes that regulates multiple aspects of fruit quality, including levels of health-promoting anthocyanins, opening the door to engineering more nutritious and ...
Wei Jian, Haohao Cao, Shu Yuan, Yudong Liu, Juanfang Lu, Wang Lu, Ning Li, Jianhui Wang, Jian Zou, Ning Tang, Chan Xu, Yulin Cheng, Yanqiang Gao, Wanpeng Xi, Mondher Bouzayen, Zhengguo Li   +15 more
doaj   +1 more source

Citrus Postharvest Green Mold: Recent Advances in Fungal Pathogenicity and Fruit Resistance

Microorganisms, 2020
As the major postharvest disease of citrus fruit, postharvest green mold is caused by the necrotrophic fungus Penicillium digitatum (Pd), which leads to huge economic losses worldwide.
Yulin Cheng, Yunlong Lin, Haohao Cao, Zhengguo Li   +3 more
doaj   +1 more source

Auxin response factor 6A regulates photosynthesis, sugar accumulation, and fruit development in tomato

Horticulture Research, 2019
Auxin response factors (ARFs) are involved in auxin-mediated transcriptional regulation in plants. In this study, we performed functional characterization of SlARF6A in tomato.
Yujin Yuan, Xin Xu, Zehao Gong, Yuwei Tang, Mengbo Wu, Fang Yan, Xiaolan Zhang, Qian Zhang, Fengqing Yang, Xiaowei Hu, Qichen Yang, Yingqing Luo, Lihua Mei, Wenfa Zhang, Cai-Zhong Jiang, Wangjin Lu, Zhengguo Li, Wei Deng   +17 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source