Results 11 to 20 of about 303,596 (194)

THERAPY OF ENDOCRINE DISEASE: Endocrine dilemma: management of Graves’ orbitopathy [PDF]

European Journal of Endocrinology, 2016
Management of Graves’ orbitopathy (GO) must be based on the correct assessment of activity and severity of the disease. Activity is usually assessed with the Clinical Activity Score, whereas severity is classified according to a European Group On Graves' Orbitopathy (EUGOGO) consensus statement as mild, moderate-to-severe, and sight-threatening ...
Irene, Campi, Guia, Vannucchi, Mario, Salvi   +2 more
openaire   +4 more sources

Alemtuzumab-Induced Graves' Disease Complicated by Pretibial Myxoedema: A Case Report. [PDF]

Case Rep Endocrinol
Background Alemtuzumab, a monoclonal antibody targeting CD52, is associated with a high incidence of secondary autoimmune disease, most commonly thyroid dysfunction. Alemtuzumab‐induced Graves’ disease (AIGD) typically follows a relapsing course and may exhibit atypical or severe phenotypes during immune reconstitution (IR). Case Presentation We report
O'Brolchain A, Reda E.
europepmc   +2 more sources

Graves' orbitopathy treated with immunosuppressive therapy and orbital radiotherapy in a tertiary care endocrine centre: case series

Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2016
Graves’ Orbitopathy (GO) is a localized entity of Graves’ disease, which is a challenging disease to treat. We describe 6 cases of moderate to severe GO who presented to our endocrine centre, with a mean age of 48.6 years and equal gender distribution ...
D. C. Kottahachchi, W. K. M. G. Amarawardena, N. A. S. Ariyawansa, S. Siyambalapitiya, K. A. Perera   +4 more
doaj   +1 more source

Anti-oxidative and Anti-Adipogenic Effects of Caffeine in an in Vitro Model of Graves' Orbitopathy [PDF]

, 2020
Oxidative stress and adipogenesis play key roles in the pathogenesis of Graves' orbitopathy (GO). In this study, the therapeutic effects of caffeine on the reduction of oxidative stress and adipogenesis were evaluated in primary cultured GO orbital ...
김재우, 고재상, 윤진숙
core   +1 more source

World thyroidology news (#4 2015)

Клиническая и экспериментальная тиреоидология, 2016
The article contains abstracts of actual modern international researches dedicated to management of various thyroid pathology and influence of accompanying states.
Yuliya Aleksandrovna Manuylova, Marina Aleksandrovna Sviridonova, Anna Evgen'evna Shvedova   +2 more
doaj   +1 more source

Modulating gut microbiota in a mouse model of Graves’ orbitopathy and its impact on induced disease

Microbiome, 2021
Background Graves’ disease (GD) is an autoimmune condition in which autoantibodies to the thyrotropin receptor (TSHR) cause hyperthyroidism. About 50% of GD patients also have Graves’ orbitopathy (GO), an intractable disease in which expansion of the ...
Sajad Moshkelgosha, Hedda Luise Verhasselt, Giulia Masetti, Danila Covelli, Filippo Biscarini, Mareike Horstmann, Anke Daser, Astrid M. Westendorf, Christoph Jesenek, Svenja Philipp, Salvador Diaz-Cano, J. Paul Banga, Daryn Michael, Sue Plummer, Julian R. Marchesi, Anja Eckstein, Marian Ludgate, Utta Berchner-Pfannschmidt, and the INDIGO consortium   +18 more
doaj   +1 more source

Color Doppler imaging of the superior ophthalmic vein in patients with Graves' orbitopathy before and after treatment of congestive disease

Clinics, 2011
OBJECTIVE: To compare superior ophthalmic vein blood flow parameters measured with color Doppler imaging in patients with congestive Graves' orbitopathy before and after treatment and in normal controls.
Mário L. R. Monteiro, Rodrigo B. S. Moritz, Hélio Angotti Neto, Joseph E. Benabou   +3 more
doaj   +1 more source

The Differential Diagnosis of Discrepant Thyroid Function Tests: Insistent Pitfalls and Updated Flow-Chart Based on a Long-Standing Experience

Frontiers in Endocrinology, 2020
Background: Discrepant thyroid function tests (TFTs) are typical of inappropriate secretion of TSH (IST), a rare entity encompassing TSH-secreting adenomas (TSHoma) and Resistance to Thyroid Hormone (RTHβ) due to THRB mutations.
Irene Campi, Irene Campi, Danila Covelli, Carla Moran, Laura Fugazzola, Laura Fugazzola, Chiara Cacciatore, Fabio Orlandi, Gabriella Gallone, Krishna Chatterjee, Paolo Beck-Peccoz, Luca Persani, Luca Persani   +12 more
doaj   +1 more source

Acute unilateral endocrine orbitopathy. A case report.

, 2015
Problemstellung: Diese Arbeit beschäftigt sich mit dem Einzelfallbericht einer erwachsenen Patientin, bei welcher aufgrund eindeutiger Symptomatik eine akute einseitige endokrine Orbitopathie diagnostiziert wurde. Ausschlaggebend für diese Erkrankung war
Steinwender, Madlen
core   +3 more sources

World thyroidology news (#2 2015)

Клиническая и экспериментальная тиреоидология, 2015
The article contains abstracts of actual modern international researches dedicated to management of various thyroid pathology and influence of accompanying ...
Yu A Manuylova, M A Sviridonova
doaj   +1 more source