Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
, 1996 To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Wenzel, Björn E. +2 more
core +1 more source
Predicting remission of Graves' disease following treatment with antithyroid drugs
, 2023 Graves' disease (GD) is among the most prevalent organ-specific diseases and is one of the most common causes of hyperthyroidism in regions with normal iodine supply.
Irina A. Kuzina +5 more
core +1 more source
Radioiodine treatment for graves’ disease: a 10-year Australian cohort study
BMC Endocrine Disorders, 2018 Background Radioactive iodine (I131) is a common definitive treatment for Graves’ Disease. Potential complications include worsening, or new development of Graves’ eye disease and development of a radiation thyroiditis.
Erin Fanning +2 more
doaj +1 more source
The rs1990760 polymorphism within the IFIH 1 locus is not associated with Graves' disease, Hashimoto's thyroiditis and Addison's disease [PDF]
, 2009 Background: Three genes have been confirmed as major joint susceptibility genes for endocrine autoimmune disease:human leukocyte antigen class II, cytotoxic T-lymphocyte antigen 4 and protein tyrosine phosphatase non-receptor type 22.
Reisch, Nicole +30 more
core +1 more source
Advances in Graves' Disease [PDF]
Journal of Thyroid Research, 2012 “From the very commencement the student should set out to witness the progress and effects of sickness and ought to persevere in the daily observation of disease during the whole period of his studies.” It was Dr. Robert J. Graves who used to pronounce this statement at the inauguration of his yearly university lectures in Dublin.
Premawardhana, L.D. (L. D.) +3 more
openaire +3 more sources
A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]
, 1994 Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Sarkar, Gobinda +3 more
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Can propylthiouracil induce autoimmune-related immunotoxicity? [PDF]
Vojnosanitetski Pregled, 2022 Introduction. The use of propylthiouracil can be associated with mild adverse reactions, but severe complications such as agranulocytosis and vasculitis can also be seen.
Bajkin Ivana +4 more
doaj +1 more source
Oftalʹmologiâ, 2019 Objective. Improving the efficiency of the operation of orbit decompression in patients with endocrine ophthalmopathy through the development of a new method for calculating an excess volume of soft tissues of the orbit. Patients and methods.
D. V. Davydov +4 more
doaj +1 more source
Thyroid Research, 2019 Background Treatment of moderate to severe Graves’ orbitopathy (GO) is based mainly on intravenous pulses of methylprednisolone. High doses of methylprednisolone can exert several adverse effects, some of which might be life-threatening. The objective of
Dorota Walasik-Szemplińska +2 more
doaj +1 more source
Tissue eosinophilia and eosinophil degranulation in Riedel's invasive fibrous thyroiditis. [PDF]
, 1996 The etiology of Riedel's invasive fibrous thyroiditis (IFT) has remained obscure. This rare disorder has been confused in the past with the more common fibrous variant of Hashimoto's disease.
A. E. Heufelder +9 more
core +1 more source