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Graves' disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is the most common cause of hyperthyroidism and occurs at all ages but especially in women of reproductive age. Graves' hyperthyroidism is caused by autoantibodies to the thyroid-stimulating hormone receptor (TSHR) that act as agonists and induce excessive ...
Davies, Terry F. +8 more
openaire +5 more sources
Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto +4 more
doaj +1 more source
Antithyroid Drug Treatment in Graves’ Disease [PDF]
Graves’ disease is associated with thyrotropin (TSH) receptor stimulating antibody, for which there is no therapeutic agent. This disease is currently treated through inhibition of thyroid hormone synthesis or destruction of the thyroid gland. Recurrence
Jae Hoon Chung
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Immunoglobulin G4-Related Thyroid Disease: A Single-Center Experience and Literature Review [PDF]
Background Immunoglobulin G4 (IgG4)-related disease is an entity that can involve the thyroid gland. The spectrum of IgG4-related thyroid disease (IgG4-RTD) includes Hashimoto thyroiditis (HT) and its fibrotic variant, Riedel thyroiditis, as well as ...
Meihua Jin +7 more
doaj +1 more source
Clinical Outcomes of Repeated Radioactive Iodine Therapy for Graves’ Disease [PDF]
Background Radioactive iodine (RAI) therapy is a successful therapeutic modality for Graves’ disease. However, RAI therapy can fail, and RAI therapy after antithyroid drugs (ATDs) has a lower remission rate.
Min Joo Kim +6 more
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Graves' disease is an autoimmune thyroid disease with several characteristic symptoms and signs. Graves' ophthalmopathy, an inflammatory disease in the orbital area, is the main extrathyroid manifestation of Graves' disease.
Herry Krisnata Ginting, Soebagijo Adi
doaj +1 more source
Programmed Cell Death-Ligand 1 (PD-L1) gene Single Nucleotide Polymorphism in Graves’ Disease and Hashimoto’s Thyroiditis in Korean Patients [PDF]
Background Programmed cell death-ligand 1 (PD-L1) has an important role in regulating immune reactions by binding to programmed death 1 (PD-1) on immune cells, which could prevent the exacerbation of autoimmune thyroid disease (AITD).
Jee Hee Yoon +7 more
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Radioiodine treatment for graves’ disease: a 10-year Australian cohort study
Background Radioactive iodine (I131) is a common definitive treatment for Graves’ Disease. Potential complications include worsening, or new development of Graves’ eye disease and development of a radiation thyroiditis.
Erin Fanning +2 more
doaj +1 more source
Switching of Hashimoto Thyroiditis Into Graves’ Disease: A Case Report and Literature Review [PDF]
Background: Hashimoto thyroiditis (HT) and Graves’ disease (GD) are autoimmune inflammatory thyroid disorders. The evolution from GD into HT is the most common scenario while the conversion from HT into GD seems to be less common. Case Presentation: A 20-
Rajab Maksoud +3 more
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Advances in Graves' Disease [PDF]
“From the very commencement the student should set out to witness the progress and effects of sickness and ought to persevere in the daily observation of disease during the whole period of his studies.” It was Dr. Robert J. Graves who used to pronounce this statement at the inauguration of his yearly university lectures in Dublin.
Premawardhana, L.D. (L. D.) +3 more
openaire +3 more sources

