Results 31 to 40 of about 703,622 (310)

Nearly Half of Patients with Anaplastic Thyroid Cancer May Be Amenable to Immunotherapy

Biomedicines
Importance: Poorly differentiated cancer (PDC) and anaplastic thyroid cancer (ATC) have an aggressive course of disease with limited treatment options. The expression of programmed cell death ligand-1 (PD-L1) has been used to determine the responses of ...
Beverley Chern, Diluka Pinto, Jeffrey Hy Lum, Rajeev Parameswaran   +3 more
doaj   +1 more source

Is There a New Road to Spinal Cord Injury Rehabilitation? A Case Report about the Effects of Driving a Go-Kart on Muscle Spasticity

Diseases, 2023
Background: Traumatic spinal cord injury (SCI) is a neurological disorder that causes a traumatic anatomical discontinuity of the spinal cord. SCI can lead to paraplegia, spastic, or motor impairments.
Giacomo Farì, Maurizio Ranieri, Riccardo Marvulli, Laura Dell’Anna, Annatonia Fai, Lucrezia Tognolo, Andrea Bernetti, Laura Caforio, Marisa Megna, Ernesto Losavio   +9 more
doaj   +1 more source

A Generalized Net Model of the Prostate Gland’s Functioning

Mathematics, 2022
Over the last 20 years, many Generalized Net (GN) models of the ways of functioning of the different systems and organs in the human body and models related to the description of biomedical processes in living organisms have been constructed.
Martin Lubich, Velimir Papazov, Elenko Popov, Radostina Georgieva, Dmitrii Dmitrenko, Borislav Bojkov, Chavdar Slavov, Peter Vassilev, Vassia Atanassova, Lyudmila Todorova, Krassimir T. Atanassov   +10 more
doaj   +1 more source

Treatment of a mixed acinar-endocrine carcinoma with uptake on 68Gallium-DOTATOC positron emission tomography-computed tomography : a case report [PDF]

, 2017
The case of a 35-year old female patient with a diagnosis of metastatic mixed acinar-endocrine carcinoma (MAEC) is investigated in the present study.
De Both, Anneleen, De Man, Marc, Geboes, Karen, Hoorens, Anne, Troisi, Roberto, Van Vlierberghe, Hans   +5 more
core   +2 more sources

A review of neuroendocrine immune system abnormalities in IBS based on the brain–gut axis and research progress of acupuncture intervention

Frontiers in Neuroscience, 2023
Irritable bowel syndrome (IBS) is a common digestive disorder observed in clinics. Current studies suggest that the pathogenesis of the disease is closely related to abnormal brain–gut interactions, hypokinesia, visceral sensory hypersensitivity in the ...
Zhangyin Sun, Zhangyin Sun, Xuejiao Wang, Xuejiao Wang, Shangsheng Feng, Chaoju Xie, Chaoju Xie, Yu Xing, Yu Xing, Liang Guo, Liang Guo, Jingyu Zhao, Changchun Ji, Changchun Ji   +13 more
doaj   +1 more source

Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]

, 2016
We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M., Cotinot, C., Evans, N.P., Fowler, P.A., MacDonald, E.S., Mandon-Pepin, B., Rhind, S., Sharpe, R.M.   +7 more
core   +2 more sources

Detection of activating estrogen receptor gene (ESR1) mutations in single circulating tumor cells [PDF]

, 2017
Purpose: Early detection is essential for treatment plans before onset of metastatic disease. Our purpose was to demonstrate feasibility to detect and monitor estrogen receptor 1 (ESR1) gene mutations at the single circulating tumor cell (CTC) level in ...
Austin, Laura, Capoluongo, Ettore, Cristofanilli, Massimo, Fortina, Paolo, Knudsen, Karen E., Mu, Zhaomei, Nguyen, Thomas, Paolillo, Carmela, Rossi, Giovanna, Schiewer, Matthew J.   +9 more
core   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Neurobiological correlates of burnout

Telangana Journal of Psychiatry, 2021
Introduction: Maslach defined burnout syndrome first time as a syndrome involving (i) exhaustion, (ii) “depersonalization” – lack of empathy for or detachment from service recipients, and (iii) a reduced sense of professional accomplishment.
Durva Balkrishna Sail, Avinash De Sousa
doaj   +1 more source

Vitamin D. a dynamic molecule. how relevant might the dynamism for a vitamin be [PDF]

, 2015
Cholecalciferol, the precursor of Vitamin D3, is a very old, highly conserved, molecule. Its presence is evident in non-mineralized 750 million-year-old living species, such as plankton.
Mazzaferro, Sandro, Pasquali, Marzia
core   +2 more sources