Results 71 to 80 of about 703,622 (310)

A Narrative Review on the Influence of Electromagnetic Fields Below 100 kHz on the Endocrine System

open access: yesApplied Sciences
Background: Extremely low-frequency electromagnetic fields (ELF-EMFs), generated mainly by power infrastructure and household devices, have raised scientific interest due to their potential impact on the endocrine system.
Piotr M. Tojza   +3 more
doaj   +1 more source

Association of the hormonal status parameters with the results of the cardiorespiratory exertion test in athletes

open access: yesКлиническая практика, 2018
The aim of this study was to identify the specifics of the endocrine system functioning in males professionally involved in sports. We have observed 70 sportsmen and 70 students of the Maritime Academy. The check-up included the following procedures: the
S. D. Megeryan
doaj   +1 more source

Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol. [PDF]

open access: yes, 2019
Dedicated breast positron emission tomography (dbPET) is an emerging technology with high sensitivity and spatial resolution that enables detection of sub-centimeter lesions and depiction of intratumoral heterogeneity.
Chien, Amy J   +10 more
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Expression of the neural cell adhesion molecule NCAM in endocrine cells [PDF]

open access: yes, 1989
We examined the expression of the neural cell adhesion molecule NCAM in a number of endocrine tissues of adult rat and in an endocrine tumor cell line. NCAM was found by immunoelectron microscopy to be present on the surface of all endocrine cells in the
Aletsee-Ufrecht, M. C.   +3 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

STRUCTURAL AND FUNCTIONAL ALTERATIONS AT THE BLOOD-BRAIN BARRIER IN A MOUSE MODEL FOR MCT8 DEFICIENCY

open access: yesIBRO Neuroscience Reports, 2023
Ana Montero-Pedrazuela   +3 more
doaj   +1 more source

Steroid Hormones and Endocrine Disruptors: Recent Advances in Receptor–Mediated Actions [PDF]

open access: yes, 2017
It has been accepted that receptor-mediated action of steroid hormones depends on both the receptor and the hormonal level. The mechanism of transcription by steroid receptors is mediated by cofactors, which function as co-activators or co ...
Indarto, Dono, Izawa, Masao
core  

DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation [PDF]

open access: yes, 2015
The acquisition of endocrine therapy resistance in estrogen receptor a (ERa) breast cancer patients represents a major clinical problem. Notch signalling has been extensively linked to breast cancer especially in patients who fail to respond to endocrine
Aifantis   +54 more
core   +3 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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