Results 261 to 270 of about 423,420 (336)
Impact of comorbidities on survival in melanoma patients. [PDF]
Buja A +10 more
europepmc +1 more source
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu +13 more
wiley +1 more source
Prolactin: A Key Immunoregulator in Viral Infections and Autoimmune Diseases. [PDF]
Asadikaram M +5 more
europepmc +1 more source
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang +12 more
wiley +1 more source
EndoCompass Project: Artificial Intelligence in Endocrinology.
Assié G +4 more
europepmc +1 more source
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li +6 more
wiley +1 more source
Beyond Tumor Immunity: The Disruption of Endocrine and Infectious Homeostasis by Immune Checkpoint Inhibitors. [PDF]
Schönberger E +9 more
europepmc +1 more source

