Results 261 to 270 of about 423,420 (336)

Impact of comorbidities on survival in melanoma patients. [PDF]

open access: yesBMC Cancer
Buja A   +10 more
europepmc   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

open access: yesAdvanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu   +13 more
wiley   +1 more source

Prolactin: A Key Immunoregulator in Viral Infections and Autoimmune Diseases. [PDF]

open access: yesInt J Endocrinol
Asadikaram M   +5 more
europepmc   +1 more source

Neuroimmune-Endocrine Modulation of T-Cell Exhaustion in Central Nervous System Parasitic Diseases: Insights from Toxoplasmosis and Neurocysticercosis

open access: diamond
Ivan Nicolás Pérez‐Osorio   +5 more
openalex   +1 more source

Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways

open access: yesAdvanced Science, EarlyView.
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang   +12 more
wiley   +1 more source

EndoCompass Project: Artificial Intelligence in Endocrinology.

open access: yesHorm Res Paediatr
Assié G   +4 more
europepmc   +1 more source

Bifurcate Regulation of Hematopoietic Homeostasis and Bone Osteogenesis by VHL‐HIF2α‐Controlled Adipocyte Function

open access: yesAdvanced Science, EarlyView.
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li   +6 more
wiley   +1 more source

Beyond Tumor Immunity: The Disruption of Endocrine and Infectious Homeostasis by Immune Checkpoint Inhibitors. [PDF]

open access: yesInt J Mol Sci
Schönberger E   +9 more
europepmc   +1 more source

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