Results 31 to 40 of about 243,452 (262)

Roles of osteoprotegerin in endocrine and metabolic disorders through receptor activator of nuclear factor kappa-B ligand/receptor activator of nuclear factor kappa-B signaling

open access: yesFrontiers in Cell and Developmental Biology, 2022
Endocrine and metabolic diseases show increasing incidence and high treatment costs worldwide. Due to the complexity of their etiology and mechanism, therapeutic strategies are still lacking.
Luodan Zhang   +5 more
doaj   +1 more source

Thyroid Hormone Availability and Action during Brain Development in Rodents

open access: yesFrontiers in Cellular Neuroscience, 2017
Thyroid hormones (THs) play an essential role in the development of all vertebrates; in particular adequate TH content is crucial for proper neurodevelopment.
Soledad Bárez-López   +3 more
doaj   +1 more source

EPA’s Endocrine Disruptor Screening Program (EDSP)

open access: yesEDIS, 2013
People have asked questions in recent years concerning the effects that certain chemicals may have on the endocrine system of humans and wildlife. Laboratory studies have produced evidence that show various chemicals disrupt the endocrine systems of ...
Frederick M. Fishel
doaj   +5 more sources

Interleukin-10 Attenuates Liver Fibrosis Exacerbated by Thermoneutrality

open access: yesFrontiers in Medicine, 2021
Background: Crosstalk between brown adipose tissue (BAT) and the liver is receiving increasing attention. This study investigated the effect of BAT dysfunction by thermoneutral (TN) housing on liver fibrosis in mice and examined the effect of secreted ...
Ha Thi Nga   +17 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Endocrine pathologies in the conditions of chemotherapy

open access: yesInfusion & Chemotherapy, 2023
BACKGROUND. Cancer is the leading cause of death in the world. Chemotherapy is the most effective and in some cases the only method of treating oncopathology.
A.V. Garnytska, O.S. Orlyk
doaj   +1 more source

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita   +5 more
wiley   +1 more source

Nationwide Big Data Studies of Endocrine Diseases Using the Korean National Health Information Database: Research Trends and Standardization of Operational Definitions [PDF]

open access: yesEndocrinology and Metabolism
The Korean National Health Information Database (NHID) is a large-scale dataset created through linkage of National Health Insurance claims with nationwide health screening records.
Sun Wook Cho   +5 more
doaj   +1 more source

Targeting trafficking as a therapeutic avenue for misfolded GPCRs leading to endocrine diseases

open access: yesFrontiers in Endocrinology, 2022
G protein-coupled receptors (GPCRs) are plasma membrane proteins associated with an array of functions. Mutations in these receptors lead to a number of genetic diseases, including diseases involving the endocrine system.
Alfredo Ulloa-Aguirre   +3 more
doaj   +1 more source

Misperception of Body Weight After Childhood Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Misperception of body weight can negatively impact the weight management efforts of childhood cancer survivors (CCSs). Both being overweight or underweight are associated with chronic health conditions commonly observed in CCS; therefore, accurate weight perception is critical for reducing long‐term health risks.
Fabiën N. Belle   +8 more
wiley   +1 more source

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